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Treatment of Alzheimer's and Dementia With the Metabolism, Infections, Nutrition, Drug Elimination (MIND) Protocol (MIND)

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ClinicalTrials.gov Identifier: NCT02260167
Recruitment Status : Completed
First Posted : October 9, 2014
Last Update Posted : May 8, 2020
Sponsor:
Information provided by (Responsible Party):
Practitioners Alliance Network

Brief Summary:
Treating with measures that may improve metabolic functioning of neurons in an integrated protocol

Condition or disease Intervention/treatment Phase
Alzheimer's Disease Dementia Other: A mix of natural treatments and medications Not Applicable

Detailed Description:

Most organ failure results in modest drops in function until over 50% of function is lost. At a certain point, even modest drops in physiologic activity result in dramatic drops in clinical function. Though less homogeneous than in other organs, clinical experience and the literature suggests a similar process occurs in the brain. The hypothesis is that by using an integrated protocol to, essentially, "tune up" neuronal function, a 5-10 % improvement in metabolic functioning may translate to significant improvement in clinical functioning. This tune-up will include "MIND":

M- Metabolism-- optimizing hormonal function I- Infections-- looking for and eliminating N- Nutritional and herbal support D- Drugs- Weaning subjects off unneeded medications

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 25 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effective Treatment of Alzheimer's and Dementia With the MIND Protocol
Actual Study Start Date : September 2014
Actual Primary Completion Date : December 2017
Actual Study Completion Date : December 2017

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Dementia

Arm Intervention/treatment
Experimental: Treatment with MIND Other: A mix of natural treatments and medications
Other Name: MIND Protocol




Primary Outcome Measures :
  1. Montreal Cognitive Assessment (MoCA) [ Time Frame: 6 months ]
    Looking to see what percent of patients show improvement


Secondary Outcome Measures :
  1. Mini Mental Status Exam (MMSE) [ Time Frame: 6 months ]
  2. Alzheimer's Disease Assessment Scale- Activities of Daily Living (ADAS-ADL) [ Time Frame: 6 months ]


Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • A diagnosis of Alzheimer's and/or dementia with an MMSE score over 12 or being ambulatory and able to travel outside the home with assistance.
  • Must have a caregiver living with them.

Exclusion Criteria:

  • Overt progressive and severe causes of secondary dementia such as metastatic brain cancers, or severe overt infectious encephalopathies or severe autoimmune illness.
  • Also, severe life threatening illnesses which would make them unlikely to be alive after 6-12 months

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02260167


Locations
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United States, Hawaii
PAN
Kailua, Hawaii, United States, 96740
Sponsors and Collaborators
Practitioners Alliance Network
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Responsible Party: Practitioners Alliance Network
ClinicalTrials.gov Identifier: NCT02260167    
Other Study ID Numbers: PAN-ALZ002
First Posted: October 9, 2014    Key Record Dates
Last Update Posted: May 8, 2020
Last Verified: May 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Additional relevant MeSH terms:
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Alzheimer Disease
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Tauopathies
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders