CIMT and Plaque Assessment Findings in Subjects Undergoing Stress Echocardiography For Risk Stratification
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|ClinicalTrials.gov Identifier: NCT02245048|
Recruitment Status : Completed
First Posted : September 19, 2014
Last Update Posted : June 10, 2019
The purpose of this research study is to determine if carotid artery ultrasound scanning can provide additional information for determining cardiovascular risk in patients.
Patients who agree to participate wil undergo non-invasive carotid intima-media thickness (CIMT) measurement and plaque assessment. Findings of CIMT will be compared to results of patient standard of care stress echocardiogram (SE) and of diastolic function.
We hypothesize tht 1) in patients undergoing SE for inappropriate or uncertain indications, CIMT and plaque assessment will provide useful risk stratification beyond use of traditional risk factors; 2) CIMT findings will correlate with results of SE in terms of exercise capacity and 3) Exercise capacity will correlate with diastolic function.
|Condition or disease||Intervention/treatment|
|Cardiovascular Risk Stratification Carotid Intima-media Thickness (CIMT) Stress Echocardiography (SE)||Other: Carotid Intima-Media Thickness (CIMT)|
|Study Type :||Observational|
|Actual Enrollment :||73 participants|
|Official Title:||Carotid Intima-Media Thickness and Plaque Assessment Findings in Subjects Undergoing Stress Echocardiography For Risk Stratification|
|Actual Study Start Date :||October 2014|
|Actual Primary Completion Date :||May 2016|
|Actual Study Completion Date :||May 2016|
Stress Echocardiography (SE)
Subjects will undergo CIMT measurements.
Other: Carotid Intima-Media Thickness (CIMT)
- % Patients w/ Abnormal IMT vs. % Patients w/ Positive Ischemia on Stress Echocardiogram [ Time Frame: Baseline ]We are comparing the % of patients with abnormal IMT defined as presence of plaque (= or >1.5mm) or CIMT >75% percentile for age, race, and gender compared to % of patients with positive ischemia on stress echocardiogram as defined by a new wall motion abnormality on echocardiogram with stress.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02245048
|United States, Arizona|
|Scottsdale, Arizona, United States, 85254|
|Principal Investigator:||Tasneem Naqvi, MD||Mayo Clinic|