Games to Overcome Late Life Depression (GOLD)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02229188|
Recruitment Status : Active, not recruiting
First Posted : September 1, 2014
Last Update Posted : January 29, 2018
|Condition or disease||Intervention/treatment||Phase|
|Major Depressive Disorder||Behavioral: Problem Solving Therapy Behavioral: Evolution Behavioral: Words||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||40 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||Single (Outcomes Assessor)|
|Primary Purpose:||Health Services Research|
|Official Title:||Games to Overcome Late Life Depression|
|Actual Study Start Date :||December 2013|
|Estimated Primary Completion Date :||March 2018|
|Estimated Study Completion Date :||March 2018|
Active Comparator: Problem Solving Therapy
Problem Solving Therapy is an evidence-based behavioral treatment for late life depression proven effective with different geriatric groups including ambulatory; medically ill; older adults with executive dysfunctions; and more recently, low-income, disabled older adults.
Behavioral: Problem Solving Therapy
Problem solving therapy is an evidence based behavioral intervention for late life depression. It consist of 8 weekly session of talk therapy, whereby the therapist helps the patient solve problems that are thought to be causing depressive symptoms.
Other Name: PST
Evolution is a plasticity intervention in the form of a video driving game that targets the cognitive conflict network.
Evo is a video game that has therapeutic elements targeting the cognitive control network. Impairment in this neural network is associated with a specific subtype of late life depression that puts people at risk for poor response to SSRIs. Evo is built from a research grade training paradigm that has shown to induce improvements in this network in healthy older adults
Placebo Comparator: Words
Words is a challenging crosswords type of game that will serve as the placebo comparator to Evo.
Words is a cognitively challenging crossword/word search type of video game that will serve as the control condition for the second phase of this project
- Change in depression over time [ Time Frame: weeks 0, 4, 8, 24 ]Hamilton Depression Rating Scale
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02229188
|United States, Washington|
|University of Washington Department of Psychiatry and Behavioral Sciences|
|Seattle, Washington, United States, 98105|
|Principal Investigator:||Patricia Arean, PhD||University of Washington|