Prediction of Fluid Responsiveness in Atrial Fibrillation Patients Who Underwent Valvular Heart Surgery: Peep-induced Increase in Central Venous Pressure vs. Passive Leg Raising
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|ClinicalTrials.gov Identifier: NCT02224378|
Recruitment Status : Completed
First Posted : August 25, 2014
Last Update Posted : April 1, 2015
|Condition or disease||Intervention/treatment||Phase|
|Valvular Heart Surgery||Procedure: peep induced CVP Procedure: passive leg raising(PLR)||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||44 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Study Start Date :||March 2012|
|Actual Primary Completion Date :||October 2014|
|Actual Study Completion Date :||October 2014|
|Experimental: peep induced CVP||Procedure: peep induced CVP|
|Active Comparator: passive leg raising(PLR)||Procedure: passive leg raising(PLR)|
- fluid responsiveness [ Time Frame: 1hr after arriving at ICU ]
- ventilator peep setting was adjusted to 0cmH2O as baseline
- Then peep was increased to 10cmH2O for 5 min.
- We set peep to baseline 0cmH2O again, making patients to semirecumbent position following passive leg raising at 30 degree for 5 min.
- After that, 300 ml of hydroxyethyl starch 130/0.4 was infused in the supine position for 10-20 min and haemodynamic variables including SVI were assessed 5 min after completion of fluid challenge.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02224378
|Korea, Republic of|
|Department of Anesthesiology & Pain Medicine, Yonsei university college of medicine|
|Seoul, Korea, Republic of, 120-752|