Sperm Pathology Samples and Morphokinetics

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details. Identifier: NCT02155179
Recruitment Status : Recruiting
First Posted : June 4, 2014
Last Update Posted : April 4, 2018
Information provided by (Responsible Party):
IVI Madrid

Brief Summary:

The embryo kinetics may be a new prognostic factor for choosing the embryos with the highest implantation potential. In order to identify the factors that may affect the rate of embryo cleavage, there are many studies about morphokinetics and culture medium, oxygen tension, oocyte quality or type of medication used for ovarian stimulation. However there are no published data with respect to the influence of semen quality in the embryo kinetic.

In this study The investigators propose that the sperm quality may has influence in the embryo division.

Condition or disease
Cylinical Embryo Oligospermia

Study Type : Observational
Estimated Enrollment : 60 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Embryo Kinetics and Sperm Quality. Depends on the Sperm Quality the Embryo Cleavage Rate?
Study Start Date : August 2014
Estimated Primary Completion Date : December 2018
Estimated Study Completion Date : December 2018

Good prognosis
Sperm samples >15mill/ml >30% progresive sperms
bad prognosis
Sperm samples <5mill/ml <5% progresive sperms

Primary Outcome Measures :
  1. embryo division in 2, 3, 4, 5, 6, 7, 8, cells and blastocyst formation [ Time Frame: between day 0 and day 5 of development ]
    Exact time of cell cleavages

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Sperms samples of assisted reproduction treatments

Inclusion Criteria:

  • Sperm samples with more than 15 mill/ml of sperms, more than 40% of mobile sperms
  • Sperm samples with less than 5 mill/ml of sperms, less than 10% of mobile sperms

Exclusion Criteria:

  • sperm samples between 5 to 15 mil/ml of sperms and between 10% to 40% of mobile sperms

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02155179

Contact: David Agudo, PhD

IVI MAdrid Not yet recruiting
Madrid, Spain, 28023
Sub-Investigator: David Agudo, PhD         
Madrid, Spain
Contact: David Agudo, PhD   
Sponsors and Collaborators
IVI Madrid
Principal Investigator: david agudo, PhD lab coordinator

Responsible Party: IVI Madrid Identifier: NCT02155179     History of Changes
Other Study ID Numbers: semen-esd
First Posted: June 4, 2014    Key Record Dates
Last Update Posted: April 4, 2018
Last Verified: April 2018

Additional relevant MeSH terms:
Infertility, Male
Genital Diseases, Male