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Effects of Yoga on Heart Rate Variability and Mood in Women

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02153385
Recruitment Status : Completed
First Posted : June 3, 2014
Last Update Posted : June 4, 2014
Information provided by (Responsible Party):
I-Hua Chu, PT, PhD, Kaohsiung Medical University

Brief Summary:

Background: Women are more likely to suffer from depression and anxiety, which have been linked to reduced heart rate variability (HRV) and increased cardiovascular morbidity and mortality. The purpose of this study was to examine the effects of an 8-week yoga program on HRV and mood in generally healthy women. The investigators hypothesized that there would be improvements in HRV and reductions in perceived stress and symptoms of depression and anxiety after the yoga intervention.

Methods: Fifty-two healthy women were randomized to either a yoga group or a control group. Participants in the yoga group completed an 8-week yoga program, which comprised a 60-minute session, twice a week. Each session consisted of breathing exercises, yoga pose practice, and supine meditation/relaxation. Participants' HRV, perceived stress, depressive symptoms, and state and trait anxiety were assessed at baseline and week 9.

Condition or disease Intervention/treatment Phase
Heart Rate Variability Other: Yoga Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 52 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effects of Yoga on Heart Rate Variability and Mood in Women: A Randomized Controlled Trial
Study Start Date : September 2010
Actual Primary Completion Date : June 2011
Actual Study Completion Date : June 2011

Arm Intervention/treatment
Experimental: Yoga group
Two yoga sessions per week for 8 weeks
Other: Yoga
Yoga program was 60 min per session, twice per week for 8 weeks. Led by an experienced yoga instructor.

No Intervention: Control group
Usual level of physical activity; no involvement in any yoga practice during the course of the study

Primary Outcome Measures :
  1. Change from baseline in heart rate variability at week 9 [ Time Frame: The ourcome measure was assessed at baseline and at week 9 ]
    Heart rate variability analysis was derived from continuous heart rate recording, at a sampling rate of 1024 Hz, using an electrocardiogram (ECG) system (MP 150, BIOPAC Systems, Goleta, CA, USA). Participants were instructed to avoid exercise one day before the assessment session and abstain from caffeinated food and beverages on the day of assessment. During the assessment, participants were instructed to relax in a supine position with no other tasks or stimulation for 20 minutes while the ECG was recording. The last 10 minutes of the ECG recording was analyzed for HRV. R-R intervals were computed and the HRV power spectrum was obtained via a fast Fourier transformation algorithm using an appropriate software program (HRV Analysis for Windows, version 1.1; Biosignal Imaging Group and Analysis, the University of Kuopio, Kuopio, Finland).

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • women
  • aged 18-50 years old
  • body mass index < 30 kg/m2

Exclusion Criteria:

  • currently engaged in regular yoga practice
  • pregnant
  • nursing
  • had physical contraindications to exercise

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02153385

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Kaohsiung Medical University
Kaohsiung, Taiwan, 807
Sponsors and Collaborators
Kaohsiung Medical University
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Principal Investigator: I-Hua Chu, PhD Kaohsiung Medical University
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Responsible Party: I-Hua Chu, PT, PhD, Assistant Professor, Kaohsiung Medical University Identifier: NCT02153385    
Other Study ID Numbers: KMU-Q099012
First Posted: June 3, 2014    Key Record Dates
Last Update Posted: June 4, 2014
Last Verified: June 2014
Keywords provided by I-Hua Chu, PT, PhD, Kaohsiung Medical University:
Yoga, heart rate variability, stress, mood, women