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Assessment of the Psychological, Cognitive and Social Resources of Applicants for Huntington's Disease and Presymptomatic Genetic Testing (PREHUNT)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified February 2013 by University Hospital, Angers.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT02134561
First Posted: May 9, 2014
Last Update Posted: May 9, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
University Hospital, Angers
  Purpose
The purpose of this study is to assess the psychological, cognitive and social resources of applicants for Huntington's Disease and Presymptomatic Testing.

Condition Intervention
Presymptomatic Huntington Disease Behavioral: psychological interview Radiation: MRI Other: cognitive tests Other: neurological tests

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care

Resource links provided by NLM:


Further study details as provided by University Hospital, Angers:

Primary Outcome Measures:
  • Change from baseline total score of the psychological Unified Huntington's Disease Rating Scale at 2 years [ Time Frame: 3 months before diagnostic (baseline) ; 2 years after diagnostic, ]

Estimated Enrollment: 25
Study Start Date: September 2013
Estimated Primary Completion Date: September 2017 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
All subjects
psychological interview, MRI, neurological tests, cognitive tests
Behavioral: psychological interview Radiation: MRI
This MRI is a specific intervention assign to the subjects of the study, that's why it is an interventionnal study
Other: cognitive tests Other: neurological tests

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Applicants for Huntington's Disease and Presymptomatic Testing
  • Aged 18 years and above
  • Huntington disease family member
  • Subject gave its written consent

Exclusion Criteria:

  • No national health insurance affiliation
  • Being under guardianship
  • Meeting brain MRI exclusion criteria (pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin, or body, Renal failure, hypersensitivity of Gadolinium) or refusing MRI.
  • Patient with movement disorder
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02134561


Locations
France
University Hospital of Angers Recruiting
Angers, Pays de la Loire, France, 49933
Contact: Philipe ALLAIN       phallain@chu-angers.fr   
Sponsors and Collaborators
University Hospital, Angers
  More Information

Responsible Party: University Hospital, Angers
ClinicalTrials.gov Identifier: NCT02134561     History of Changes
Other Study ID Numbers: 2013-A00088-37
First Submitted: April 10, 2014
First Posted: May 9, 2014
Last Update Posted: May 9, 2014
Last Verified: February 2013

Additional relevant MeSH terms:
Huntington Disease
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Dementia
Chorea
Dyskinesias
Movement Disorders
Heredodegenerative Disorders, Nervous System
Neurodegenerative Diseases
Genetic Diseases, Inborn
Cognition Disorders
Neurocognitive Disorders
Mental Disorders


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