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National Egyptian Network Pediatric Stroke and Hemiplegia Registry

This study is currently recruiting participants. (see Contacts and Locations)
Verified May 2014 by Ain Shams University
Information provided by (Responsible Party):
Sahar M.A. Hassanein, MD, Ain Shams University Identifier:
First received: April 15, 2014
Last updated: May 1, 2014
Last verified: May 2014
Our aim is to establish multi-center national Egyptian database of information about cerebrovascular stroke and hemiplegia in infants and children from 0 to 18 years of age.

Stroke With Hemiparesis
Perinatal Stroke
Focal Neurologic Deficits

Study Type: Observational [Patient Registry]
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Target Follow-Up Duration: 10 Years
Official Title: National Egyptian Network Pediatric Stroke and Hemiplegia Registry

Resource links provided by NLM:

Further study details as provided by Ain Shams University:

Primary Outcome Measures:
  • Survival or neurologic deficit after acute cerebrovascular stroke. [ Time Frame: participants will be followed for the duration of hospital stay, an expected average of 6 weeks ]
    Children with acute stroke will be followed till either death or discharge from hospital, all clinical, radiological and therapeutic data will be collected.

Secondary Outcome Measures:
  • Long term neurological deficit [ Time Frame: 12 months ]
    Post-stroke pediatric gross and fine motor function will be assessed.

Estimated Enrollment: 1000
Study Start Date: January 2014
Estimated Study Completion Date: December 2021
Estimated Primary Completion Date: January 2020 (Final data collection date for primary outcome measure)
Pediatric Stroke and Hemiplegia
Any infant or child with acute stroke or hemiplegia

Detailed Description:

Aims: An open-ended multi-center, national Egyptian study to collect and analyze data for children with cerebrovascular stroke and hemiplegia .

Participants: Eligible infants and children with stroke and hemiplegia.

DESIGN: This study is a prospective cohort study.

Primary outcome measure: Initial acute stroke clinical and radiological presentation, recurrent stroke, mortality, and neurologic deficits in the acute stage, participants will be followed for the duration of hospital stay, an expected average of 6 weeks


Ages Eligible for Study:   up to 18 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
All children from birth to 18 years of age with acute stroke presented by focal neurological signs confirmed by neuroradiology CT or MRI. All children with hemiplegia till the age of 18 years.

Inclusion Criteria:

  • Focal neurological deficit of acute onset lasting greater than 20 minutes. And CT or MRI showing infarct in location consistent with neurological signs and symptoms
  • Hemiplegia

Exclusion Criteria:

  1. Cerebral haemorrhage not associated with ischemic infarct.
  2. Hypoxic ischemic event with diffuse or bilateral infarction alone.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT02129491

Contact: Sahar MA Hassanein, MD, PhD 201223183943

Pediatric Department, Children's Hospital, Faculty of Medicine, Ain Shams University Recruiting
Cairo, Abassia, Egypt, 11381
Contact: Mohsen S Elalfy, MD, PhD   
Principal Investigator: Sahar MA Hassanein, MD, PhD         
Sponsors and Collaborators
Ain Shams University
Study Chair: Sahar MA Hassanein, MD, PhD Pediatric Department, Children's Hospital, Faculty of Medicine, Ain Shams University
  More Information

Additional Information:
Responsible Party: Sahar M.A. Hassanein, MD, Professor of Pediatrics, Ain Shams University Identifier: NCT02129491     History of Changes
Other Study ID Numbers: NENPSHR
Study First Received: April 15, 2014
Last Updated: May 1, 2014

Keywords provided by Ain Shams University:
Congenital stroke

Additional relevant MeSH terms:
Neurologic Manifestations
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Signs and Symptoms
Paralysis processed this record on April 26, 2017