Working… Menu

Effect of Adaptive Training for Balance Recovery

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02126488
Recruitment Status : Active, not recruiting
First Posted : April 30, 2014
Last Update Posted : August 31, 2020
National Institute on Aging (NIA)
Information provided by (Responsible Party):
Tanvi Bhatt, University of Illinois at Chicago

Brief Summary:
The long-term objective of this research is a prophylactic approach that can reduce the incidence of falls and the resulting injuries among older adults at risk and thus reduce its escalating medical cost. This project explores perturbation training through the use of treadmill device and a motor learning approach, in which experience with slip-like perturbation generated by that treadmill is used to prepare the motor system to develop and then put to use fall-resisting skills outside of training environment (cross-environment transfer). The computer-controlled treadmill is portable, safe and easy to operate, thus conducive for use in clinics or community centers. The study logically builds on and complements the team's previous and current research programs, and will further test that after such a single session, older adults at risk can retain such cross-environment transfer and reduce their likelihood of falls in everyday living for the next 6 to 12 months. Finally, the study will explore that such reduction of falls does not come merely from these persons' familiarity with the training or testing setup, protocol and environments.

Condition or disease Intervention/treatment Phase
Balance, Postural Prevention, Accident Behavioral: treadmill slip perturbation Behavioral: treadmill training placebo Behavioral: observation training Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 308 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Prevention
Official Title: Perturbation Training for Fall-risk Reduction Among Older Adults
Study Start Date : June 2014
Estimated Primary Completion Date : June 2021
Estimated Study Completion Date : June 2021

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Falls

Arm Intervention/treatment
Experimental: treadmill perturbation
treadmill slip perturbation
Behavioral: treadmill slip perturbation
Group A will receive perturbation training on a treadmill with precisely controlled slip-like displacements and then encounter an unannounced novel slip during over-ground walking.

Placebo Comparator: treadmill placebo
treadmill training placebo
Behavioral: treadmill training placebo
An age-matched control group (Group B) will receive only placebo training (on the same treadmill for the same duration but without perturbation) but encounter an identical novel slip during their over-ground walking.

Sham Comparator: observation
observation training
Behavioral: observation training
An age-matched observation-training group (Group C) will watch a training video and slides. When exposed to an identical novel slip in over-ground walking, they will know where and how the slip is going to occur and how to resist a fall.

Primary Outcome Measures :
  1. Fall incidence [ Time Frame: 1 year ]

Secondary Outcome Measures :
  1. Dynamic stability [ Time Frame: 6 months ]
    The dynamic stability will be evaluated based on the dynamic relationship of motion state (i.e., the combination of position and velocity) between the center of mass and the base of support. It will be calculated as the shortest distance from the instantaneous motion state of the center of mass to the threshold against backward fall. It is a dimensionless variable.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   65 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Subjects with no known history of musculoskeletal, neurological, cardiovascular, or pulmonary impairment that may affect their ability to perform the testing procedures will be included.

Exclusion Criteria:

  • Ultrasound calcaneus bone mineral density T score < -2.5 (osteoporotic)
  • Mini-Mental State exam score < 25 (cognitive impairment)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02126488

Layout table for location information
United States, Illinois
Clinical Gait and Movement Analysis Laboratory
Chicago, Illinois, United States, 60612
Sponsors and Collaborators
University of Illinois at Chicago
National Institute on Aging (NIA)
Layout table for investigator information
Principal Investigator: Yi-Chung Pai, PhD University of Illinois at Chicago
Layout table for additonal information
Responsible Party: Tanvi Bhatt, Associate Professor, University of Illinois at Chicago Identifier: NCT02126488    
Other Study ID Numbers: 2000-0788
R01AG044364 ( U.S. NIH Grant/Contract )
First Posted: April 30, 2014    Key Record Dates
Last Update Posted: August 31, 2020
Last Verified: August 2020
Keywords provided by Tanvi Bhatt, University of Illinois at Chicago:
treadmill training