United Coronary Biobanks (UNICORN)
|ClinicalTrials.gov Identifier: NCT02126150|
Recruitment Status : Completed
First Posted : April 29, 2014
Last Update Posted : December 8, 2015
The UNICORN consists of two collaborating biobanks, one in Utrecht and one in Singapore. From these two sites we include all patients who undergo a coronary catheterization for any reason.
At the moment of catheterization we draw blood, which will be stored in a biobank and we collect clinical characteristics. Patients are followed-up for 5 years for the occurrence of major cardiovascular events.
By including from two sites in the world we include 4 major ethnic groups: Caucasians, Chinese, Indians and Malays. We aim at including at least 2000 patients per ethnic group.
Our hypothesis is that there are differences in the risk factor burden, clinical presentation of CAD, and biochemical patterns in the blood among the ethnic groups.
Furthermore, this biobank offers a platform for multi-ethnic biomarker discovery.
|Condition or disease|
|Coronary Artery Disease Acute Coronary Syndrome Myocardial Infarction Stable Angina|
|Study Type :||Observational|
|Actual Enrollment :||2000 participants|
|Official Title:||United CORoNary Biobanks|
|Study Start Date :||September 2010|
|Primary Completion Date :||December 2015|
|Study Completion Date :||December 2015|
- All-cause death [ Time Frame: 5 years ]
- Major cardiovascular events [ Time Frame: 5 years ]
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02126150
|National University Hospital|
|Singapore, Singapore, 119074|