Central Meditation and Imagery Therapy for Augmentation of Borderline Personality Disorder Treatment
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|ClinicalTrials.gov Identifier: NCT02125942|
Recruitment Status : Completed
First Posted : April 29, 2014
Last Update Posted : May 12, 2017
Borderline personality disorder is a severe psychiatric disorder marked by emotional instability, difficulty with interpersonal relationships, and self-harming behaviors. Despite receiving psychotherapy for borderline personality disorder, studies show that patient recovery is slow, and there is a high rate of self injury and suicide attempts early in treatment. There is thus a clear need to provide therapies to augment psychotherapy. We will conduct a pilot trial to determine whether a 6-week Central Meditation and Imagery Therapy (CMIT) is feasible for subjects with borderline personality disorder to undergo when added on to psychotherapy treatment. CMIT is a non-validated therapy that combines principles of mindfulness with meditation techniques and guided imagery. Sessions led by a trained clinician in a group setting once a week, and participants are asked to complete daily home practice.
The trial will involve 16 participants, all currently undergoing psychotherapy for borderline personality disorder. Participants will be randomly assigned to either a CMIT group that lasts 6 weeks, or a wait list group. Those in the wait list group will be able to receive CMIT after 6 weeks. All participants will continue to receive psychotherapy throughout the trial.
During the trial, we will also obtain preliminary data to help understand whether CMIT may result in psychological benefits for participants. This will include measuring the pulse in order to determine variation in beat to beat intervals of the heart during psychological tests, and filling out questionnaires before and after participation in CMIT.
|Condition or disease||Intervention/treatment||Phase|
|Borderline Personality Disorder||Behavioral: Central Meditation and Imagery Therapy||Phase 1 Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||15 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Pilot Study of Central Meditation and Imagery Therapy for Borderline Personality Disorder|
|Study Start Date :||April 2014|
|Actual Primary Completion Date :||September 2015|
|Actual Study Completion Date :||September 2015|
Central Meditation and Imagery Therapy
Behavioral: Central Meditation and Imagery Therapy
mindfulness, guided imagery, meditation
No Intervention: wait list
- Borderline Symptoms [ Time Frame: 6 weeks ]Borderline Symptom List
- Depression [ Time Frame: 6 weeks ]Quick Inventory of Depressive Symptoms
- Anxiety [ Time Frame: 6 weeks ]Trait Anxiety Inventory
- Positive Affect [ Time Frame: 6 weeks ]Positive and Negative Affect Scale
- Heart rate variability [ Time Frame: 6 weeks ]Resting heart rate variability
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02125942
|United States, California|
|University of California, Los Angeles|
|Los Angeles, California, United States, 90095|
|Principal Investigator:||Felipe A Jain, MD||University of California, Los Angeles|