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Trial record 2 of 604 for:    Personality Disorders

Central Meditation and Imagery Therapy for Augmentation of Borderline Personality Disorder Treatment

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ClinicalTrials.gov Identifier: NCT02125942
Recruitment Status : Completed
First Posted : April 29, 2014
Last Update Posted : May 12, 2017
Sponsor:
Information provided by (Responsible Party):
Felipe Jain, University of California, Los Angeles

Brief Summary:

Borderline personality disorder is a severe psychiatric disorder marked by emotional instability, difficulty with interpersonal relationships, and self-harming behaviors. Despite receiving psychotherapy for borderline personality disorder, studies show that patient recovery is slow, and there is a high rate of self injury and suicide attempts early in treatment. There is thus a clear need to provide therapies to augment psychotherapy. We will conduct a pilot trial to determine whether a 6-week Central Meditation and Imagery Therapy (CMIT) is feasible for subjects with borderline personality disorder to undergo when added on to psychotherapy treatment. CMIT is a non-validated therapy that combines principles of mindfulness with meditation techniques and guided imagery. Sessions led by a trained clinician in a group setting once a week, and participants are asked to complete daily home practice.

The trial will involve 16 participants, all currently undergoing psychotherapy for borderline personality disorder. Participants will be randomly assigned to either a CMIT group that lasts 6 weeks, or a wait list group. Those in the wait list group will be able to receive CMIT after 6 weeks. All participants will continue to receive psychotherapy throughout the trial.

During the trial, we will also obtain preliminary data to help understand whether CMIT may result in psychological benefits for participants. This will include measuring the pulse in order to determine variation in beat to beat intervals of the heart during psychological tests, and filling out questionnaires before and after participation in CMIT.


Condition or disease Intervention/treatment Phase
Borderline Personality Disorder Behavioral: Central Meditation and Imagery Therapy Phase 1 Phase 2

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 15 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: Pilot Study of Central Meditation and Imagery Therapy for Borderline Personality Disorder
Study Start Date : April 2014
Actual Primary Completion Date : September 2015
Actual Study Completion Date : September 2015

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: meditation
Central Meditation and Imagery Therapy
Behavioral: Central Meditation and Imagery Therapy
mindfulness, guided imagery, meditation

No Intervention: wait list
waiting list



Primary Outcome Measures :
  1. Borderline Symptoms [ Time Frame: 6 weeks ]
    Borderline Symptom List


Secondary Outcome Measures :
  1. Depression [ Time Frame: 6 weeks ]
    Quick Inventory of Depressive Symptoms

  2. Anxiety [ Time Frame: 6 weeks ]
    Trait Anxiety Inventory

  3. Positive Affect [ Time Frame: 6 weeks ]
    Positive and Negative Affect Scale


Other Outcome Measures:
  1. Heart rate variability [ Time Frame: 6 weeks ]
    Resting heart rate variability



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Meeting the diagnostic criteria for BPD according to DSM-IV criteria
  • Meeting the diagnostic criteria for BPD based on the Diagnostic Interview for Borderline - Revised
  • Currently receiving psychotherapy.
  • English language proficiency to understand written and oral communication

Exclusion Criteria:

  • Active suicidality or suicidal intent as identified on the Columbia Suicide Severity Rating Scale
  • Suicide attempt within the past month

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02125942


Locations
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United States, California
University of California, Los Angeles
Los Angeles, California, United States, 90095
Sponsors and Collaborators
University of California, San Francisco
Investigators
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Principal Investigator: Felipe A Jain, MD University of California, Los Angeles

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Responsible Party: Felipe Jain, Clinical Instructor of Psychiatry, University of California, Los Angeles
ClinicalTrials.gov Identifier: NCT02125942     History of Changes
Other Study ID Numbers: CMIT1044
First Posted: April 29, 2014    Key Record Dates
Last Update Posted: May 12, 2017
Last Verified: May 2017
Keywords provided by Felipe Jain, University of California, Los Angeles:
Borderline Personality Disorder
Additional relevant MeSH terms:
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Disease
Personality Disorders
Borderline Personality Disorder
Pathologic Processes
Mental Disorders