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Trial record 2 of 530 for:    Recruiting, Not yet recruiting, Available Studies | "Platelet Aggregation Inhibitors"

Research of Resistance to Antiplatelet Agents and Development of Tailored Treatment Model for Patients With Coronary Artery Disease

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ClinicalTrials.gov Identifier: NCT02121054
Recruitment Status : Recruiting
First Posted : April 23, 2014
Last Update Posted : September 25, 2017
Sponsor:
Information provided by (Responsible Party):
Young-Hak Kim, MD, PhD, Asan Medical Center

Brief Summary:
The purpose of this study is to evaluate the prognosis of patients with resistance to antiplatelet agent and develop tailored treatment model for patients with coronary artery disease.

Condition or disease
Cardiovascular Diseases Coronary Artery Disease

Study Type : Observational
Estimated Enrollment : 2000 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Research of Resistance to Antiplatelet Agents and Development of Tailored Treatment Model for Patients With Coronary Artery Disease
Study Start Date : September 2013
Estimated Primary Completion Date : September 2020
Estimated Study Completion Date : December 2020

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. Major adverse event [ Time Frame: 2 year ]
    Major adverse event : overall mortality, cardiovascular mortality, target vessel revascularization


Secondary Outcome Measures :
  1. Biomarker [ Time Frame: 2 year ]
    homocysteine, Lp(a), fibrinogen, PAI-1, NTpro-BNP, hs-CRP, matrix metalloproteinase-9, soluble CD40L, IL-6, serum amyloid A, AGE



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Ages Eligible for Study:   20 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients with coronary artery disease, Patients with peripheral artery disease
Criteria

Inclusion Criteria:

  • Age 〉20
  • Patients with coronary artery disease
  • Patients with peripheral artery disease

Exclusion Criteria:

  • Renal dysfunction
  • Hepatic dysfunction
  • Major surgery planned within 1 year
  • Malignant tumor
  • History of gastrointestinal bleeding
  • low or high platelet count

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02121054


Contacts
Contact: Young-Hak Kim, MD, PhD mdyhkim@amc.seoul.kr

Locations
Korea, Republic of
Asan Medical Center Recruiting
Seoul, Songpa-Gu, Korea, Republic of
Contact: Young-Hak Kim, MD, PhD    82-2-3010-3955    mdyhkim@amc.seoul.kr   
Principal Investigator: Young-Hak Kim, MD,PhD         
Sponsors and Collaborators
Young-Hak Kim, MD, PhD

Responsible Party: Young-Hak Kim, MD, PhD, MD, PhD, Asan Medical Center
ClinicalTrials.gov Identifier: NCT02121054     History of Changes
Other Study ID Numbers: 2013-0873
First Posted: April 23, 2014    Key Record Dates
Last Update Posted: September 25, 2017
Last Verified: September 2017

Keywords provided by Young-Hak Kim, MD, PhD, Asan Medical Center:
Antiplatelet Agents
Drug Resistance

Additional relevant MeSH terms:
Cardiovascular Diseases
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases
Platelet Aggregation Inhibitors