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Trial record 7 of 8 for:    Parkinson's | "vitamin d"

Strength and Balance in Gender- and Age-Matched Controls (VITDC)

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ClinicalTrials.gov Identifier: NCT02110875
Recruitment Status : Completed
First Posted : April 10, 2014
Last Update Posted : October 20, 2014
Sponsor:
Information provided by (Responsible Party):
Amie Peterson, MD, Oregon Health and Science University

Brief Summary:
The purpose of this study is to learn more about balance and strength in an elderly population (60 and older). Data will be compared between controls and the age/gender- matched PD participants in study "The Effects of vitamin D on Balance in Parkinson's disease" (OHSU IRB # 6482). Specifically a t-test will be used to compare total work and total power on leg extension and flexion, composite SOT score conditions 1-3 and 4-6, response strength and latency on MCT, and turn duration from the iMOBILITY between the two groups.

Condition or disease
Healthy Volunteers

Detailed Description:

Inclusion Criteria:

  • Over the age of 59
  • Gender and Age-Matched (within 3 years) of main protocol participants

Exclusion Criteria:

  • Parkinson's disease diagnosis
  • Significant cognitive deficits.
  • Another neurological or orthopedic deficit that in the investigator's opinion would have a significant impact on gait and cognition (e.g. stroke, fracture).

This study involves one visit to Oregon Health & Science University. The study visit will last approximately 2 hours.

Measurements:

  1. The participant's balance will be assessed by having them stand on a platform and completing mental tasks such as naming the alphabet backwards. They will be asked to have their eyes open on some tasks and closed on other tasks. For safety, they will wear a harness like those used by rock climbers.
  2. The participant's ability to move and balance will be measured by putting six sensors on their bodies (both wrists, both ankles, chest, and back). Each sensor is about the size and weight of a deck of cards. To measure movement and balance, participants will rise from a chair, walk three feet, turn around, walk back to the chair, and sit down.
  3. The participant's strength will be evaluated using a machine that resembles a stationary exercise bike. They will have one leg and foot strapped onto the machine. Participants will then be asked to flex and extend their leg as quickly as possible five times. This will be repeated with the other leg.

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Study Type : Observational
Actual Enrollment : 25 participants
Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Strength and Balance in Gender- and Age-Matched Controls: SubStudy to "The Effects of Vitamin D on Balance in Parkinson's Disease"
Study Start Date : June 2013
Actual Primary Completion Date : February 2014
Actual Study Completion Date : February 2014

Resource links provided by the National Library of Medicine


Group/Cohort
CONTROLS
Age- and Gender-Matched Controls



Primary Outcome Measures :
  1. Strength (BIODEX) [ Time Frame: Visit 1 ]
    The participant's strength will be evaluated using a machine that resembles a stationary exercise bike. They will have one leg and foot strapped onto the machine. Participants will then be asked to flex and extend their leg as quickly as possible five times. This will be repeated with the other leg.


Secondary Outcome Measures :
  1. Balance (SOT) [ Time Frame: Visit 1 ]
    The participant's balance will be assessed by having them stand on a platform and completing mental tasks such as naming the alphabet backwards. They will be asked to have their eyes open on some tasks and closed on other tasks. For safety, they will wear a harness like those used by rock climbers.



Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healthy Elderly (over 59 years old) without Parkinson's disease or Parkinsonism.
Criteria

Inclusion Criteria:

  • Over the age of 59
  • Gender and Age-Matched (within 3 years) of main protocol participants

Exclusion Criteria:

  • Parkinson's disease diagnosis
  • Significant cognitive deficits.
  • Another neurological or orthopedic deficit that in the investigator's opinion would have a significant impact on gait and cognition (e.g. stroke, fracture).

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02110875


Locations
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United States, Oregon
Oregon Health & Science University
Portland, Oregon, United States, 97239
Sponsors and Collaborators
Oregon Health and Science University
Investigators
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Principal Investigator: Amie L Peterson, MD Oregon Health and Science University