Edessy ICSI Outcome Embryo Score (EIOS) Efficacy
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|ClinicalTrials.gov Identifier: NCT02082288|
Recruitment Status : Completed
First Posted : March 10, 2014
Results First Posted : October 16, 2014
Last Update Posted : January 26, 2015
|Condition or disease||Intervention/treatment||Phase|
|Infertility||Other: Edessy ICSI Outcome Embryo Score||Phase 1 Phase 2|
A total of 243 infertile couples underwent long GnRH agonist protocol in the ART unit, International Islamic Center for Population Studies and Research (IICPSR), Al-Azhar University.
Embryos which reached the two cell stage at 25-27 hr were classified as EC, and the remaining as Non Early Cleavage embryos (NEC). Embryos were assessed again at 64-68 hours post-ICSI for day three embryo morphology score (Loi et al.,2008). The best two or three embryos, according to day 3 embryo morphology were transferred. Each patient was given a score according to EIOS (female age, number of retrieved oocytes, number of EC embryos, number of good quality embryos and number of embryos transferred).
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||243 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Supportive Care|
|Official Title:||Edessy ICSI Outcome Embryo Score (EIOS) Efficacy|
|Study Start Date :||December 2010|
|Actual Primary Completion Date :||September 2012|
|Actual Study Completion Date :||September 2012|
Experimental: Edessy ICSI Outcome Embryo Score
Other: Edessy ICSI Outcome Embryo Score
Age (ys) >35 (0) 30-35 (1) <30 (2) No of retrived oocyte <5 (0) 5-9 (1) ≥ 10 (2) No of EC embryos <2 (0) 2-4 (1) >4 (2) No of good quality embryos <3 (0) 3-5 (1) >5 (2) No of embryos transferred -------- (0) ≤2 (1) >2 (2)
- Clinical Pregnancy [ Time Frame: 6 weeks ]A clinical pregnancy will be determined by identifying the presence of a gestational sac at six weeks gestation on transvaginal ultrasonography.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02082288
|International Islamic Center for Population Studies and Research (IICPSR), Al-Azhar university|
|Principal Investigator:||Mahmoud Edessy, MD||Al-Azhar University|
|Principal Investigator:||Abd-Elnasr M Ali, MD||Al-Azhar University|
|Study Director:||Ahmed Fata, MD||Al-Azhar University|
|Study Chair:||Wael M Hamed, MSc||Al-Azhar University|