Admission HbA1C in Aneurysmal Subarachnoid Hemorrhage
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|ClinicalTrials.gov Identifier: NCT02081820|
Recruitment Status : Completed
First Posted : March 7, 2014
Last Update Posted : March 18, 2015
|Condition or disease|
|Hyperglycemia Aneurysmal Subarachnoid Hemorrhage|
In patients suffering from aneurysmal subarachnoid hemorrhage (aSAH), hyperglycemia is considered an adverse prognostic factor. Glycated hemoglobin (or HbA1c) can be measured to estimate the average plasma glucose concentration over prolonged periods of time, thus determination of glycated hemoglobin at admission after aSAH serves as an approximation of blood glucose levels in the weeks preceding aneurysm rupture.
In this patient registry admission HbA1c within 72 hours after confirmed aneurysmal subarachnoid hemorrhage in patients aged over 18 years is determined and correlated with clinical course and neurological outcome after 6 month as determined by modified Rankin score. Additionally, patients are monitored for incidence of delayed cerebral ischemia (DCI) and the incidence of new infarction on the discharge ct scan attributable to DCI. General treatment of cerebral aneurysm and subarachnoid hemorrhage in all patients follows international guidelines.
|Study Type :||Observational [Patient Registry]|
|Actual Enrollment :||89 participants|
|Target Follow-Up Duration:||6 Months|
|Official Title:||Observational Study on the Prognostic Relevance of Admission Glycated Hemoglobin (HbA1C) in Patients With Aneurysmal Subarachnoid Hemorrhage|
|Study Start Date :||July 2012|
|Actual Primary Completion Date :||December 2014|
|Actual Study Completion Date :||December 2014|
aneurysmal subarachnoid hemorrhage
observational, no intervention
- modified Rankin score [ Time Frame: 6 month after discharge ]
- Incidence of DCI related new infarction on discharge ct scan [ Time Frame: at discharge, approx. 14-21days after admission ]Incidence of new infarction on discharge ct scan not attributable to causes other then DCI.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02081820
|Department of Neurosurgery, Heinrich-Heine-University Düsseldorf|
|Düsseldorf, NRW, Germany, 40225|
|Principal Investigator:||Kerim Beseoglu, M.D.||Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf|