Reflexive Coughing Force in Severe Aspirators
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|ClinicalTrials.gov Identifier: NCT02080988|
Recruitment Status : Completed
First Posted : March 7, 2014
Last Update Posted : November 5, 2015
|Condition or disease|
Severe aspiration with a compromised cough function can be a risk factor of aspiration pneumonia.
Reflexive coughing can be tested by administration of citric acid via a nebulizer. The objective of this study is to measure the cough force produced via citric acid inhalation challenge, and determine if those with severe aspiration with severe dysphagia have more weak cough force during reflexive cough testing that those post-stroke patients with no signs of aspiration or dysphagia after stroke.
We also aimed to measure the strenght of the respiratory measures with the use of surface EMG.
|Study Type :||Observational|
|Actual Enrollment :||20 participants|
|Official Title:||Cross Sectional Evaluation of Coughing Force in Stroke Patients With Severe Aspiration|
|Study Start Date :||October 2013|
|Actual Primary Completion Date :||September 2014|
|Actual Study Completion Date :||October 2014|
Stroke patients with dysphagia with severe aspiration
Non aspirating, no dysphagia group
Stroke patients with no dysphagia and no evidence of aspiration
- Coughing force [ Time Frame: baseline one time ]Coughing force as assessed by reflexive cough test
- Coughing force during voluntary coughing [ Time Frame: baseline one time ]
- Spirometry findings (Forced vital capacity, forced expiratory volume at one second) [ Time Frame: baseline one time ]
- Maximal inspiratory and expiratory pressure [ Time Frame: baseline one time ]
- Root mean square values of respiratory muscles [ Time Frame: baseline one time ]
- Diaphragm excursion as assessed by M mode sonography [ Time Frame: baseline one time ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02080988
|Korea, Republic of|
|Bucheon St Mary's Hospital|
|Bucheon, Korea, Republic of|
|Principal Investigator:||Sun Im, Md PhD||The Catholic University of Korea|
|Study Chair:||Geun Young Park, MD PhD||The Catholic University of Korea|