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Metabolic Syndrome Cohort in Korea

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ClinicalTrials.gov Identifier: NCT02077530
Recruitment Status : Withdrawn
First Posted : March 4, 2014
Last Update Posted : November 10, 2020
Sponsor:
Information provided by (Responsible Party):
Soon Jun Hong, Korea University Anam Hospital

Brief Summary:
Patients with metabolic syndrome living in Seoul area are included in this prospective registry for more than 10 years. All enrolled patients undergo thorough medical history survey. Enrolled patients will have coronary CT, 2D echocardiogram, treadmill test, pulse wave velocity, augmentation index, carotid intima-media thickness, and abdominal fat mass evaluation. Moreover, lipid profiles and inflammatory markers such as hsCRP, IL-6, TNF-alpha, VCAM-1, ICAM-1, adiponectin, MMP-9 will be measured. All participants will repeat the test and survey every year in Korea University Hospital.

Condition or disease
Metabolic Syndrome

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Study Type : Observational [Patient Registry]
Actual Enrollment : 0 participants
Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 10 Years
Study Start Date : November 2013
Estimated Primary Completion Date : November 2023
Estimated Study Completion Date : November 2023

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. Cardiovascular events [ Time Frame: 10 years ]
    Cardiovascular events such as fatal and non-fatal myocardial infarction, heart failure, need for coronary and peripheral revascularization, stroke, all-cause death, and cardiac death.



Information from the National Library of Medicine

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Ages Eligible for Study:   30 Years to 64 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients with metabolic syndrome living in Seoul area
Criteria

Inclusion Criteria: 3 out of 5 criteria

  • Central obesity: Men ≥ 90 cm Women ≥ 85 cm
  • Plasma triglycerides ≥ 150 mg/dL
  • HDL cholesterol Men < 40 mg/dL, Women < 50 mg/dL
  • Blood pressure ≥130/85 mm Hg (or treatment for hypertension)
  • Fasting plasma glucose ≥ 100 mg/dL
  • Age between 30 to 64
  • Consent to our registry protocol

Exclusion Criteria:

  • Patients who could not undergo coronary CT, 2D echocardiogram, treadmill test, and pulse wave velocity.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02077530


Locations
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Korea, Republic of
Korea University Anam Hospital Metabolic Syndrome Research Center
Seoul, Korea, Republic of, 136-705
Sponsors and Collaborators
Korea University Anam Hospital
Additional Information:

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: Soon Jun Hong, Associate Professor, Korea University Anam Hospital
ClinicalTrials.gov Identifier: NCT02077530    
Other Study ID Numbers: MS in KUMC
First Posted: March 4, 2014    Key Record Dates
Last Update Posted: November 10, 2020
Last Verified: November 2020
Keywords provided by Soon Jun Hong, Korea University Anam Hospital:
Patients with metabolic syndrome age between 30 to 64: Central obesity (Men ≥ 90 cm Women ≥ 85 cm), Plasma triglycerides ≥ 150 mg/dL
HDL cholesterol Men < 40 mg/dL, Women < 50 mg/dL, Blood pressure ≥130/85 mm Hg (or treatment for hypertension),
Fasting plasma glucose ≥ 100 mg/dL
Additional relevant MeSH terms:
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Metabolic Syndrome
Syndrome
Disease
Pathologic Processes
Insulin Resistance
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases