Imaging Study of Neurovascular Coupling in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) (NEUROVASCAD)
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Ages Eligible for Study:
18 Years to 60 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
CADASIL patients compared to age-matched controls (two groups)
CADASIL group: typical NOTCH3 mutation, age less than 60 years, rankin score at 0-1, active social insurance
MRI contra-indications and use of any treatment known to interfere with neurovascular coupling, pregnancy, lack of informed consent