Association of Periostin Levels and Chronic Sinusitis
The purpose of this study is to see if a protein in blood, called periostin, can determine if patients have chronic sinusitis. This protein is in everyone's body, but the level of the protein may indicate certain conditions such as chronic sinusitis. The investigators are interested in testing levels of periostin to see if they are higher or lower than patients without chronic sinusitis, just as periostin is higher in patients with asthma. All patients enrolled in this study will have chronic sinusitis without asthma.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Association of Periostin Levels and Chronic Sinusitis|
- Difference in circulating serum periostin levels pre and post sinus surgery [ Time Frame: 10-15 weeks ] [ Designated as safety issue: No ]Serum collected prior to and following sinus surgery will be analyzed for concentrations of the protein periostin.
Biospecimen Retention: Samples Without DNA
Serum and paraffin embedded nasal polyp tissue samples
|Study Start Date:||September 2014|
|Estimated Primary Completion Date:||September 2016 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT02071667
|Contact: John Steinkefirstname.lastname@example.org|
|United States, Virginia|
|University of Virginia||Recruiting|
|Charlottesville, Virginia, United States, 22908|
|Contact: John W Steinke, PhD|