Association of Periostin Levels and Chronic Sinusitis
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ClinicalTrials.gov Identifier: NCT02071667
Recruitment Status :
(Unable to recruit/enroll subjects for study.)
The purpose of this study is to see if a protein in blood, called periostin, can determine if patients have chronic sinusitis. This protein is in everyone's body, but the level of the protein may indicate certain conditions such as chronic sinusitis. The investigators are interested in testing levels of periostin to see if they are higher or lower than patients without chronic sinusitis, just as periostin is higher in patients with asthma. All patients enrolled in this study will have chronic sinusitis without asthma.
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Ages Eligible for Study:
18 Years to 65 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Subjects who are recommended for sinus surgery as part of their care who self report no asthma.
Patients with sinus disease which requires surgical intervention
Ability to understand and give informed consent
Previous diagnosis of asthma
Positive methacholine challenge at screening
Diagnosis of cystic fibrosis
Concomitant use of systemic corticosteroids (except for those prescribed as part of standard pre-surgical treatment)