Association of Periostin Levels and Chronic Sinusitis
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT02071667
Recruitment Status :
(Unable to recruit/enroll subjects for study.)
The purpose of this study is to see if a protein in blood, called periostin, can determine if patients have chronic sinusitis. This protein is in everyone's body, but the level of the protein may indicate certain conditions such as chronic sinusitis. The investigators are interested in testing levels of periostin to see if they are higher or lower than patients without chronic sinusitis, just as periostin is higher in patients with asthma. All patients enrolled in this study will have chronic sinusitis without asthma.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Layout table for eligibility information
Ages Eligible for Study:
18 Years to 65 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Subjects who are recommended for sinus surgery as part of their care who self report no asthma.
Patients with sinus disease which requires surgical intervention
Ability to understand and give informed consent
Previous diagnosis of asthma
Positive methacholine challenge at screening
Diagnosis of cystic fibrosis
Concomitant use of systemic corticosteroids (except for those prescribed as part of standard pre-surgical treatment)