An Assessment of the Prevalence of Spatial Neglect in Stroke Survivors With Aphasia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02068664
Recruitment Status : Completed
First Posted : February 21, 2014
Last Update Posted : August 21, 2017
Information provided by (Responsible Party):
Kessler Foundation

Brief Summary:
The purpose of this study is to determine if stroke survivors with aphasia have spatial neglect (Phase 1). If they are determined to have the condition Phase 2 will be offered: which is prism adaptation treatment. This is a pilot study that will be performed with 4-5 subjects.

Condition or disease Intervention/treatment
Spatial Neglect Aphasia Stroke Behavioral: prism adaptation treatment

Detailed Description:
Spatial neglect is a disorder that may occur after a brain injury such as stroke. Spatial neglect may affect stroke recovery. One example of this heterogeneous condition: Individuals with spatial neglect often pay more attention to one side of what they are looking at, even though they have no difficulty seeing. The study investigators would like to screen stroke survivors with aphasia because they may also have spatial neglect (right neglect after left hemisphere stroke), which is said by the literature to occur in 25% of cases. If it is identified, a treatment approach will be offered, to attempt to remediate the condition using prism goggles, following a prism treatment protocol based on previous studies.

Study Type : Observational
Actual Enrollment : 60 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: An Assessment of the Prevalence of Spatial Neglect in Stroke Survivors With Aphasia With Option of Prism Adaptation Treatment (PAT) Protocol
Study Start Date : February 2014
Actual Primary Completion Date : December 2016
Actual Study Completion Date : December 2016

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Group/Cohort Intervention/treatment
prism adaptation treatment
Behavioral: prism adaptation treatment
Prism goggles shift the image one sees toward the left (because the thicker portion of the glass lens is on the right). This will change the perception of where the image is in space, causing the person to adapt. The after-effects of the treatment is what is important. It has been shown to make it easier for people to move in the right space (if have right neglect) or improves ability to complete other functional tasks.

Primary Outcome Measures :
  1. Kessler Foundation Neglect Assessment Process [ Time Frame: 2 weeks ]
    a performance based and behavioral measure for spatial neglect that utilizes and standardizes the administration of the Catherine Bergego Scale (CBS)

Secondary Outcome Measures :
  1. Behavior Inattention Test [ Time Frame: 2 weeks ]
    Conventional subtest, a set of paper and pencil test for spatial neglect

  2. Barthel Index [ Time Frame: 2 weeks ]
    A functional independence assessment of daily tasks

  3. University of Alabama at Birmingham (UAB) Life Space assessment [ Time Frame: 2 weeks ]
    a self graded assessment on community mobility and participation

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Stroke survivors with aphasia and spatial neglect

Inclusion Criteria:

  • A stroke survivor with aphasia who is a member at the Adler Aphasia Center

Exclusion Criteria:

  • Has a history of brain tumor, head injury with loss of consciousness, dementia, alzheimers

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02068664

United States, New Jersey
Adler Aphasia Center
Maywood, New Jersey, United States, 07607
Sponsors and Collaborators
Kessler Foundation
Principal Investigator: Kimberly Hreha, OT Kessler Foundation/Kessler Institute for Rehabilitation
Principal Investigator: A.M. Barrett, M.D. Kessler Foundation

Additional Information:
Responsible Party: Kessler Foundation Identifier: NCT02068664     History of Changes
Other Study ID Numbers: R-802-13
First Posted: February 21, 2014    Key Record Dates
Last Update Posted: August 21, 2017
Last Verified: August 2017

Keywords provided by Kessler Foundation:
spatial neglect

Additional relevant MeSH terms:
Perceptual Disorders
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Speech Disorders
Language Disorders
Communication Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
Signs and Symptoms