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Giant Intracranial Aneurysm Registry

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ClinicalTrials.gov Identifier: NCT02066493
Recruitment Status : Active, not recruiting
First Posted : February 19, 2014
Last Update Posted : January 11, 2018
Sponsor:
Collaborator:
Charite University, Berlin, Germany
Information provided by (Responsible Party):
Dr. med. Julius Dengler, Charite University, Berlin, Germany

Brief Summary:
The purpose of this study is to generate detailed insight into which therapies of giant intracranial aneurysms are being conducted, to document the natural history and the outcome of treatment over 5 years after inclusion into the Registry and to follow imaging data of giant aneurysms over years after diagnosis.

Condition or disease
Intracranial Aneurysms

  Show Detailed Description

Study Type : Observational [Patient Registry]
Actual Enrollment : 362 participants
Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 5 Years
Official Title: Giant Intracranial Aneurysm Registry
Actual Study Start Date : December 5, 2008
Estimated Primary Completion Date : September 30, 2022
Estimated Study Completion Date : September 30, 2022

Resource links provided by the National Library of Medicine


Group/Cohort
conservative management
neither surgical nor endovascular management
endovascular management
endovascular management
surgical management
surgical management



Primary Outcome Measures :
  1. aneurysm rupture rate - diagnosed radiologically (e.g. by CT) or clinically [ Time Frame: 5 years ]

Secondary Outcome Measures :
  1. health status of the patient quantified by modified Rankin Scale in combination with a basic neurological exam [ Time Frame: 5 years ]


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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
primary care clinic
Criteria

Inclusion Criteria:

  • diagnosis of a giant intracranial aneurysm

Exclusion Criteria:

  • age younger than 18

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02066493


Locations
Austria
Department of Neurosurgery, Medical University Vienna
Vienna, Austria
Finland
Department of Neurosurgery, Helsinki University Central
Helsinki, Finland
France
Department of Neuroradiology, University Hospital
Toulouse, France
Germany
Department of Neurology - Charité Berlin
Berlin, Germany
Department of Neurosurgery, Charité Berlin
Berlin, Germany
Department of Neurosurgery and Neuroradiology, Klinikum Deggendorf
Deggendorf, Germany
Department of Neurosurgery, University of Freiburg
Freiburg, Germany
Department of Neurosurgery - University of Greifswald
Greifswald, Germany
Department of Neurosurgery - University of Goettingen
Göttingen, Germany
Department of Neurosurgery - University of Hamburg
Hamburg, Germany
Department of Neurosurgery, Friedrich-Schiller-University
Jena, Germany
Department of Neuroradiology, University of Leipzig
Leipzig, Germany
Department of Neurosurgery - Technical University of Munich
Munich, Germany
Department of Neurosurgery - University of Regensburg
Regensburg, Germany
Institut für Klinische Epidemiologie und Biometrie der Universität Wuerzburg
Wuerzburg, Germany
Italy
Department of Neuroradiology, Ospedale Niguarda Ca' Granda
Milano, Italy
Japan
Department of Neurosurgery, Jikei University
Tokio, Japan
Netherlands
Department of Neurosurgery, University Hospital
Utrecht, Netherlands
Russian Federation
Department of Neurosurgery, Burdenko Neurosurgical Institute
Moscow, Russian Federation
Switzerland
Department of Neurosurgery, Kantonsspital Aarau
Aarau, Switzerland
Department of Neurosurgery - University of Geneva
Geneva, Switzerland
Department of Neuroradiology - Klinikum Hirslanden
Zurich, Switzerland
Department of Neurosurgery, University Hospital of Zurich
Zurich, Switzerland
Sponsors and Collaborators
Dr. med. Julius Dengler
Charite University, Berlin, Germany
Investigators
Study Chair: Julius Dengler, MD Charite University, Berlin, Germany
Study Director: Peter Vajkoczy, Prof., MD Charite University, Berlin, Germany
Study Director: Veit Rohde, Prof., MD University of Goettingen
Study Director: Peter Heuschmann, Prof., MD University of Wuerzburg
Study Director: Bernhard Meyer, Prof., MD Technische Universität München
Study Director: Daniel Ruefenacht, Prof., MD Klinikum Hirslanden Zurich
Study Director: Matthias Endres, Prof., MD Charite University, Berlin, Germany

Additional Information:
Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Dr. med. Julius Dengler, MD, Charite University, Berlin, Germany
ClinicalTrials.gov Identifier: NCT02066493     History of Changes
Other Study ID Numbers: Giant
CS-2009-13 ( Other Grant/Funding Number: Center for Stroke Research - Berlin )
First Posted: February 19, 2014    Key Record Dates
Last Update Posted: January 11, 2018
Last Verified: January 2018

Keywords provided by Dr. med. Julius Dengler, Charite University, Berlin, Germany:
giant intracranial aneurysm

Additional relevant MeSH terms:
Aneurysm
Intracranial Aneurysm
Vascular Diseases
Cardiovascular Diseases
Intracranial Arterial Diseases
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases