This site became the new ClinicalTrials.gov on June 19th. Learn more.
Show more
ClinicalTrials.gov Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...
ClinicalTrials.gov Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more...
ClinicalTrials.gov Menu
Give us feedback

Study of Pain Processing in Experienced Yoga Practitioners

This study has been completed.
Sponsor:
Collaborators:
National Institute of Neurological Disorders and Stroke (NINDS)
National Institute of Nursing Research (NINR)
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( National Center for Complementary and Integrative Health (NCCIH) )
ClinicalTrials.gov Identifier:
NCT02055235
First received: February 4, 2014
Last updated: July 6, 2017
Last verified: October 12, 2016
  Purpose

Background:

- Different people perceive the same pain differently. Mood, attention, stress, and personality affect how we feel pain. Researchers want to know whether people who do yoga perceive pain differently than people who do not practice yoga, meditation, or martial arts. They also want to study if cortisol, a stress hormone, relates to pain or brain differences.

Objective:

- To study the effects of yoga on the body s stress response, pain perception, and the brain s structure and pain response.

Eligibility:

  • Right-handed adults 30 years and older who practice yoga regularly.
  • Healthy right-handed volunteers 30 years and older who do at least mild exercise but no yoga or martial arts.

Design:

  • Visit 1: Participants will be screened with medical history and physical exam. They will have blood and urine tests and electrocardiogram to measure heart activity.
  • At home, participants will wear a heart monitor for 1 day and collect 5 saliva samples daily for seven days.
  • Visit 2: Participants will undergo tests in a chair or in a mock MRI machine. They will lie on a table that slides into a cylinder.
  • A heating device will be placed on their leg and heated periodically for few seconds at a time.
  • They will give saliva samples.
  • Heart rate, respiration, etc. will be monitored.
  • They will fill out questionnaires.
  • Visit 3: Participants will answer questions and repeat Visit 2 tests. Tests will be done in the real MRI machine. The scanner makes loud knocking sounds. Participants will get earplugs. Participants will be in the scanner about 1 hour with a coil over their head.

Condition
Pain

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Pain Processing and Pain Control in Experienced Yoga Practitioners

Further study details as provided by National Institutes of Health Clinical Center (CC) ( National Center for Complementary and Integrative Health (NCCIH) ):

Primary Outcome Measures:
  • Pain perception (pain ratings) [ Time Frame: 22 months ]

Secondary Outcome Measures:
  • Brain acivations, brain anatomy, autonomic response, cortisol [ Time Frame: 22 months ]

Enrollment: 47
Study Start Date: January 27, 2014
Study Completion Date: October 12, 2016
Primary Completion Date: October 19, 2015 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   30 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria
  • FOR YOGA PRACTITIONERS:

You may qualify if you are:

  • at least 30 years old
  • an experienced yoga practitioner and practice regularly
  • fluent in English
  • right-handed
  • in good health

You may not qualify if you:

  • have a major medical condition
  • suffer from chronic pain
  • are pregnant or breast-feeding
  • have a fear of enclosed spaces (claustrophobia)

FOR HEALTHY CONTROLS:

You may qualify if you are:

  • at least 30 years old
  • fluent in English
  • right-handed
  • in good health

You may not qualify if you:

  • practice yoga, meditation, or martial arts
  • have a major medical condition
  • suffer from chronic pain
  • are pregnant or breast-feeding

have a fear of enclosed spaces (claustrophobia)

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT02055235

Locations
United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
Sponsors and Collaborators
National Center for Complementary and Integrative Health (NCCIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Institute of Nursing Research (NINR)
Investigators
Principal Investigator: Mary C Bushnell, Ph.D. National Center for Complementary and Integrative Health (NCCIH)
  More Information

Publications:
Responsible Party: National Center for Complementary and Integrative Health (NCCIH)
ClinicalTrials.gov Identifier: NCT02055235     History of Changes
Other Study ID Numbers: 140054
14-AT-0054
Study First Received: February 4, 2014
Last Updated: July 6, 2017

Keywords provided by National Institutes of Health Clinical Center (CC) ( National Center for Complementary and Integrative Health (NCCIH) ):
Brain
Pain
Yoga

ClinicalTrials.gov processed this record on July 21, 2017