A Prospective, Multicenter All Comers Study of Phasix Mesh for Ventral or Incisional Hernia Repair

Inclusion Criteria:

• Subject or subject's legally authorized representative must be willing to give written informed consent
• Subject must be diagnosed with ventral or incisional hernia
• Subject must be willing to undergo open ventral hernia repair and be able to undergo all other study procedures as outlined in this protocol.

Exclusion Criteria:

• Subject is an active smoker (if attempts to quit smoking within two weeks of surgery have failed and the patient is still an active smoker at the time of surgery).
• Subject's hernia has recurred four or more times.
• Subject's body mass index (BMI) >40 kg/m2.
• Subject has peritonitis.
• Subject is on or suspected to be placed on chemotherapy medications during any part of the study.
• Chronic steroid use or immunosuppression drugs (> 6 months).
• Subject has cirrhosis, and/or ascites.
• Subject is American Society of Anesthesiology Class 4 or 5.
• Subject is pregnant or planning to become pregnant during the course of the study.
• Subject is known to be infected with human immunodeficiency virus (HIV).
• Subject has a life expectancy of less than 2 years at the time of enrollment.
• Subject has been treated with an investigational product in the past 30 days.
• Subject is part of the site personnel directly involved with this study
• Subject has a known allergy to tetracycline hydrochloride or kanamycin sulfate, the test device or its component materials.
• Subject has any condition that in the opinion of the Investigator would preclude the use of the study device, or preclude the subject from completing the follow-up requirements