A Pharmacokinetic and Pharmacogenetic Study in Patients Receiving Sulfamethoxazole-trimethoprim Therapy
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ClinicalTrials.gov Identifier: NCT02045160
Recruitment Status : Unknown
Verified July 2014 by National Taiwan University Hospital. Recruitment status was: Recruiting
In this study, we aim to investigate the incidence of the adverse reactions, the effectiveness and the gene polymorphism associated with the plasma level of sulfamethoxazole-trimethoprim and their metabolites (including N4-acetyl-sulfamethoxazole, sulfamethoxazole hydroxylamine and sulfamethoxazole-nitroso). And we also aim to investigate the factors associated with the sulfamethoxazole-trimethoprim induced acute psychosis.
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Ages Eligible for Study:
20 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients who are treated in the National Taiwan University Hospital
males and females aged 20 years or older
using oral or intravenous form of sulfamethoxazole-trimethoprim