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Racing and Crowded Thoughts in Mood Disorders

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ClinicalTrials.gov Identifier: NCT02036606
Recruitment Status : Recruiting
First Posted : January 15, 2014
Last Update Posted : August 28, 2018
Sponsor:
Information provided by (Responsible Party):
University Hospital, Strasbourg, France

Brief Summary:
Racing thoughts relate to subjective acceleration of thinking which has been essentially associated with manic episodes in bipolar disorder. Qualitatively, the phenomenology of racing thoughts in major depression seems to differ from rumination and pure manic racing thoughts: thoughts of all kinds accumulate in the patient's head. Recent qualitative evidence is consistent with the existence of these two kinds of "thought overactivity" related to mood disorders. In order to evaluate this and better understand the psychopathological and cognitive mechanisms that underlie thought overactivity in mood disorders, we have created a 34-item self-questionnaire - the Racing and Crowded Thoughts Questionnaire (RCTQ) and a number of neuropsychological tasks (time perception, cognitive flexibility). Also, given the relationship between mood disorders and creativity, it is likely that thought overactivity is related to increased creativity. We aim at evaluating this relationship through the French version of the Cognitive Processes Associated with Creativity scale (CPAC).

Condition or disease Intervention/treatment
Bipolar Disorder Behavioral: questionary

Study Type : Observational
Estimated Enrollment : 220 participants
Observational Model: Other
Time Perspective: Other
Official Title: Psychopathological and Cognitive Mechanisms of Racing and Crowded Thoughts in Mood Disorders
Actual Study Start Date : April 2014
Estimated Primary Completion Date : April 2019
Estimated Study Completion Date : April 2020

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
mood disorders
Questionary and neuropsychological tasks will be administered
Behavioral: questionary
control
Questionary and neuropsychological tasks will be administered
Behavioral: questionary



Primary Outcome Measures :
  1. Validation of the scale of Crowded Racing Thoughts Questionary = (RCTQ scale that assesses the two forms of racing thoughts) [ Time Frame: one week ]
    Demonstrated a two-factor structure (crowded and racing) assessment concurrent and discriminant validity.


Secondary Outcome Measures :
  1. Evaluation of executive and temporal mechanisms involved in racing thoughts [ Time Frame: one week ]

Other Outcome Measures:
  1. Validation of the French version of the scale Cognitive Processes Associated with Creativity or CPAC scale (scale that assesses creativity) [ Time Frame: one week ]


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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Primary care clinic
Criteria

Inclusion Criteria:

  • Bipolar disorder or depressive disorder
  • 18 -65 years old

Exclusion Criteria:

  • neurological conditions or sequelae
  • substance abuse in the last 10 months
  • schizophrenia
  • ADHD
  • Borderline personality disorder
  • Pregnant women- Subjects under legal supervision

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02036606


Contacts
Contact: Dimitri Sanchez drci@chru-strasbourg.fr

Locations
France
Service de psychiatrie 2 , Les Hôpitaux Universitaires de Strasbourg Recruiting
Strasbourg, Alsace, France, 67091
Contact: Gilles Bertschy, PHD MD       gilles.bertschy@chru-strasbourg.fr   
Principal Investigator: Gilles Bertschy, PHD MD         
Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
Principal Investigator: Gilles Bertschy, PHDMD Les Hôpitaux Universitaires de Strasbourg

Responsible Party: University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier: NCT02036606     History of Changes
Other Study ID Numbers: 5582
First Posted: January 15, 2014    Key Record Dates
Last Update Posted: August 28, 2018
Last Verified: August 2018

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
Disease
Bipolar Disorder
Mood Disorders
Pathologic Processes
Bipolar and Related Disorders
Mental Disorders