Transpulmonary Thermodilution Measurements in Patients With Heart Diseases
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|ClinicalTrials.gov Identifier: NCT02035007|
Recruitment Status : Completed
First Posted : January 14, 2014
Last Update Posted : June 26, 2015
|Condition or disease||Intervention/treatment||Phase|
|Heart Diseases||Device: PiCCO Catheter (Pulsiocath 5F)||Phase 4|
- How do PiCCO and PAC (pulmonary artery catheter) derived hemodynamic variables change in different cardiac pathologies?
- How do PiCCO hemodynamic variables compare to transthoracic echocardiographic parameters in different cardiac pathologies?
- How does GEDV (global enddiastolic volume) correlate with left ventricles end-diastolic volume (LVEDV) assessed by LV (left ventricle) ventriculography and echocardiography?
- How do PiCCO cardiac function variables (GEF [global ejection fraction]; CFI [cardiac function index]) correlate with LV dP/dt max, LVEF (left ventricular ejection fraction) assessed by LV ventriculography and echocardiography, LVFAC (left ventricular fractional area of change), LV stroke work index (LVSWI) and cardiac power (CP)?
- How does GEDV compare to LVEDV and left ventricular end-diastolic pressure (LVEDP) as assessed by the pulmonary artery occlusion pressure (PAOP)?
- How does right ventricular function influence GEDV, GEF and CFI?
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||70 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Transpulmonary Thermodilution Measurements in Patients With Heart Diseases|
|Study Start Date :||July 2009|
|Actual Primary Completion Date :||December 2014|
|Actual Study Completion Date :||December 2014|
Experimental: LV-EF > 50%
PiCCO catheter analysis of patients with coronary heart disease without impaired left ventricular function [LV-EF > 50%]
Device: PiCCO Catheter (Pulsiocath 5F)
Measuring of PiCCO derived values
Other Name: Pulsiocath 5F, Pulsion Medical Systems, Munich, Germany
- Cardiac Output, Preload values (GEDV) [ Time Frame: Day 1 only ]Outcome measure is obtained during PiCCO measurement and left/right heart catherization, respectively ("point-of-care" measurement). There is no follow-up examination thereafter.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02035007
|Medical Intensive Care Unit, University Hospital of Zurich|
|Zurich, Switzerland, 8091|
|Principal Investigator:||Marco Maggiorini, Prof MD||University Hospital Zurich, Medical Intensive Care Unit|