Working...
ClinicalTrials.gov
ClinicalTrials.gov Menu
Trial record 79 of 990 for:    Heparin sodium

Clinical Outcomes About Heparin Surface Modified Aspheric Lens

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT02026765
Recruitment Status : Completed
First Posted : January 3, 2014
Last Update Posted : December 9, 2015
Sponsor:
Information provided by (Responsible Party):
A-Yong Yu, Wenzhou Medical University

Brief Summary:
The purpose of this study is to obverse the effect of this type lens in the same as traditional aspheric intraocular lens at the same time, whether can further improve the effects of operation.

Condition or disease Intervention/treatment Phase
Inflammatory Reaction Device: traditional lens Device: heparin surface modified aspheric lens Not Applicable

Detailed Description:
  1. Heparin surface treatment lens can reduce inflammatory reaction.
  2. Modified aspheric lens are more in line with human optical properties than the traditional aspheric lens.
  3. To obverse the effect of this type lens in the same as traditional aspheric intraocular lens at the same time, whether can further improve the effects of operation.
  4. After one day, one week, one month, three month follow-up,Key observation on the flare, the optical quality, contrast sensitivity and other parameters.Study the postoperative inflammatory reaction with test group lens,and the impact on the visual quality.

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 20 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Clinical Outcomes About Heparin Surface Modified Aspheric Lens
Study Start Date : November 2013
Actual Primary Completion Date : October 2014
Actual Study Completion Date : October 2014

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Blood Thinners

Arm Intervention/treatment
Heparin Surface Modified Aspheric Lens
Heparin Surface Modified Aspheric Lens
Device: heparin surface modified aspheric lens
the other eye implant heparin surface modified aspheric lens

traditional lens
traditional Aspheric lens
Device: traditional lens
A random eyes with traditional lens




Primary Outcome Measures :
  1. flare value in the anterior chamber after surgery [ Time Frame: six months ]
    use Laser Flare Meter to measure the flare in the anterior chamber to evaluate postoperative ocular inflammatory reaction


Secondary Outcome Measures :
  1. the ocular and the anterior corneal aberration after surgery [ Time Frame: six months ]
    use wavefront aberrometer to measure the ocular and the anterior corneal aberration to evaluate postoperative ocular optical quality



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Cataract patients

Exclusion Criteria:

  • Eyed patients

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02026765


Locations
Layout table for location information
China, Zhejiang
The Affiliated Eye hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China, 325000
Sponsors and Collaborators
Wenzhou Medical University
Investigators
Layout table for investigator information
Study Director: AYong Yu, MD. PhD. Wenzhou Medical University

Layout table for additonal information
Responsible Party: A-Yong Yu, Dr, Wenzhou Medical University
ClinicalTrials.gov Identifier: NCT02026765     History of Changes
Other Study ID Numbers: 5AT-6M
First Posted: January 3, 2014    Key Record Dates
Last Update Posted: December 9, 2015
Last Verified: December 2015

Additional relevant MeSH terms:
Layout table for MeSH terms
Inflammation
Pathologic Processes
Heparin
Calcium heparin
Anticoagulants
Fibrinolytic Agents
Fibrin Modulating Agents
Molecular Mechanisms of Pharmacological Action