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Speed of Processing Training to Improve Cognition in Traumatic Brain Injury and Mild Cognitive Impairment

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ClinicalTrials.gov Identifier: NCT02020564
Recruitment Status : Recruiting
First Posted : December 25, 2013
Last Update Posted : July 2, 2017
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The purpose of this research study is to investigate the effectiveness of a technique designed to improve processing speed (i.e. the amount of time it takes to process information) in a Traumatic Brain Injury (TBI) population. The study is designed to study how well this technique can help people with TBI increase their processing speed and their ability to function better in everyday life.

Condition or disease Intervention/treatment
Traumatic Brain Injury Mild Cognitive Impairment Behavioral: Speed of Processing Training

Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 80 participants
Intervention Model: Crossover Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Speed of Processing Training to Improve Cognition in Traumatic Brain Injury and Mild Cognitive Impairment: A Randomized Clinical Trial
Study Start Date : December 2012
Estimated Primary Completion Date : December 2017
Estimated Study Completion Date : December 2017

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Experimental: Computerized Tests Behavioral: Speed of Processing Training


Outcome Measures

Primary Outcome Measures :
  1. Improving Processing Speed [ Time Frame: 6-months ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 59 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • diagnosis of Traumatic Brain Injury or Mild cognitive impairment
  • Fluent in English
  • processing speed impairment

Exclusion Criteria:

  • prior stroke or neurological disease
  • currently taking steroids and/or benzodiazepines
  • history of significant pyschiatric illness (for example, bipolar disorder, schizophrenia, or pyschosis) or a current diagnosis of Major Depressive Disorder, Schizophrenia, Epilepsy, Bipolar Disorder
  • significant alcohol or drug abuse history
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02020564


Locations
United States, New Jersey
Kessler Foundation Research Center Recruiting
West Orange, New Jersey, United States, 07052
Contact: Belinda Washington, B.A.    973-324-3528    bwashington@kesslerfoundation.org   
Principal Investigator: Nancy Chiaravalloti, PhD         
Sponsors and Collaborators
Kessler Foundation
More Information

Responsible Party: Nancy Chiaravalloti, Director, Neuropsychology & Neuroscience; Director, Traumatic Brain Injury Research, Kessler Foundation
ClinicalTrials.gov Identifier: NCT02020564     History of Changes
Other Study ID Numbers: R-755-12
First Posted: December 25, 2013    Key Record Dates
Last Update Posted: July 2, 2017
Last Verified: June 2017

Keywords provided by Nancy Chiaravalloti, Kessler Foundation:
Processing Speed
Cognition
Intervention
Traumatic Brain Injury
Mild Cognitive Impairment

Additional relevant MeSH terms:
Wounds and Injuries
Brain Injuries
Brain Injuries, Traumatic
Cognitive Dysfunction
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Craniocerebral Trauma
Trauma, Nervous System
Cognition Disorders
Neurocognitive Disorders
Mental Disorders
Methamphetamine
Central Nervous System Stimulants
Physiological Effects of Drugs
Sympathomimetics
Autonomic Agents
Peripheral Nervous System Agents
Dopamine Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Adrenergic Agents
Adrenergic Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Dopamine Uptake Inhibitors