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Speed of Processing Training to Improve Cognition in Traumatic Brain Injury and Mild Cognitive Impairment

This study is currently recruiting participants.
See Contacts and Locations
Verified June 2017 by Nancy Chiaravalloti, Kessler Foundation
Sponsor:
Information provided by (Responsible Party):
Nancy Chiaravalloti, Kessler Foundation
ClinicalTrials.gov Identifier:
NCT02020564
First received: December 19, 2013
Last updated: June 30, 2017
Last verified: June 2017
  Purpose
The purpose of this research study is to investigate the effectiveness of a technique designed to improve processing speed (i.e. the amount of time it takes to process information) in a Traumatic Brain Injury (TBI) population. The study is designed to study how well this technique can help people with TBI increase their processing speed and their ability to function better in everyday life.

Condition Intervention
Traumatic Brain Injury Mild Cognitive Impairment Behavioral: Speed of Processing Training

Study Type: Interventional
Study Design: Intervention Model: Crossover Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Speed of Processing Training to Improve Cognition in Traumatic Brain Injury and Mild Cognitive Impairment: A Randomized Clinical Trial

Resource links provided by NLM:


Further study details as provided by Nancy Chiaravalloti, Kessler Foundation:

Primary Outcome Measures:
  • Improving Processing Speed [ Time Frame: 6-months ]

Estimated Enrollment: 80
Study Start Date: December 2012
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: December 2017 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Computerized Tests Behavioral: Speed of Processing Training

  Eligibility

Ages Eligible for Study:   18 Years to 59 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • diagnosis of Traumatic Brain Injury or Mild cognitive impairment
  • Fluent in English
  • processing speed impairment

Exclusion Criteria:

  • prior stroke or neurological disease
  • currently taking steroids and/or benzodiazepines
  • history of significant pyschiatric illness (for example, bipolar disorder, schizophrenia, or pyschosis) or a current diagnosis of Major Depressive Disorder, Schizophrenia, Epilepsy, Bipolar Disorder
  • significant alcohol or drug abuse history
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT02020564

Locations
United States, New Jersey
Kessler Foundation Research Center Recruiting
West Orange, New Jersey, United States, 07052
Contact: Belinda Washington, B.A.    973-324-3528    bwashington@kesslerfoundation.org   
Principal Investigator: Nancy Chiaravalloti, PhD         
Sponsors and Collaborators
Kessler Foundation
  More Information

Responsible Party: Nancy Chiaravalloti, Director, Neuropsychology & Neuroscience; Director, Traumatic Brain Injury Research, Kessler Foundation
ClinicalTrials.gov Identifier: NCT02020564     History of Changes
Other Study ID Numbers: R-755-12
Study First Received: December 19, 2013
Last Updated: June 30, 2017

Keywords provided by Nancy Chiaravalloti, Kessler Foundation:
Processing Speed
Cognition
Intervention
Traumatic Brain Injury
Mild Cognitive Impairment

Additional relevant MeSH terms:
Mild Cognitive Impairment
Wounds and Injuries
Brain Injuries
Cognition Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Craniocerebral Trauma
Trauma, Nervous System
Neurocognitive Disorders
Mental Disorders
Methamphetamine
Central Nervous System Stimulants
Physiological Effects of Drugs
Sympathomimetics
Autonomic Agents
Peripheral Nervous System Agents
Dopamine Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Adrenergic Agents
Adrenergic Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Dopamine Uptake Inhibitors

ClinicalTrials.gov processed this record on September 21, 2017