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Dexmedetomidine and Renal Transplants

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02019121
Recruitment Status : Active, not recruiting
First Posted : December 24, 2013
Last Update Posted : July 7, 2020
Sponsor:
Information provided by (Responsible Party):
University of California, Davis

Brief Summary:
Investigators aim to retrospectively research patients undergoing renal transplants that received dexmedetomidine perioperatively to see if dexmedetomidine use protects renal function. Investigators hope to elucidate any association between renal transplant patients and perioperative dexmedetomidine administration, these include (but are not limited to) UOP, Cr/GFR, morbidity, mortality, in hospital complications and failure rate. Investigators will research both living and cadaveric renal transplants.

Condition or disease
Renal Failure

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Study Type : Observational
Estimated Enrollment : 5000 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Dexmedetomidine and Renal Transplants
Study Start Date : October 2013
Estimated Primary Completion Date : January 2021
Estimated Study Completion Date : June 2021

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. Cr/GFR improvement, postoperative mortality/morbidity (within 30 days) and overall complications [ Time Frame: 5 years ]

Secondary Outcome Measures :
  1. Graft failure, length of hospital stay (LOS), length of ICU stay, re-admission rate, infections, pulmonary complications. [ Time Frame: 5 years ]

Other Outcome Measures:
  1. length of intubation time, and length of ventilation time [ Time Frame: 5 years ]


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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Renal transplant patients
Criteria

Inclusion Criteria: Patients greater than or equal to 18 years old that underwent renal transplant at UC Davis Medical Center -

Exclusion Criteria: Patients that did not undergo renal transplants and patients less than 18 years old will be excluded from the study.

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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02019121


Locations
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United States, California
UC Davis Health System
Sacramento, California, United States, 95817
Sponsors and Collaborators
University of California, Davis
Investigators
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Principal Investigator: Hong Liu, M.D. University of California, Davis
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Responsible Party: University of California, Davis
ClinicalTrials.gov Identifier: NCT02019121    
Other Study ID Numbers: 521455
First Posted: December 24, 2013    Key Record Dates
Last Update Posted: July 7, 2020
Last Verified: July 2020
Additional relevant MeSH terms:
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Renal Insufficiency
Kidney Diseases
Urologic Diseases