French Observatory of Familial Hypercholesterolemia in Cardiology (FH Care)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02013713
Recruitment Status : Suspended (Lack of enrollment)
First Posted : December 17, 2013
Last Update Posted : November 24, 2017
Information provided by (Responsible Party):
French Cardiology Society

Brief Summary:

The Family Hypercholesterolemia remains poorly diagnosed disease with an outlet sometimes suboptimal care. However, the Family Hypercholesterolemia exposes patients concerned at increased cardiovascular risk.

The frequency of familial hypercholesterolemia in cardiologic is little studied and remains unknown, and there is little data on the profile of patients, diagnostic methods and management.

Main objectives:

  • Establish a monitoring patients with hypercholesterolemia Family cardiology in France
  • Characterize the Family hypercholesterolemia in cardiology, including assessing the frequency of the most severe forms, which are at higher cardiovascular risk.

Condition or disease
Familial Hypercholesterolemia

Study Type : Observational
Estimated Enrollment : 200 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: French Observatory of Familial Hypercholesterolemia in Cardiology
Study Start Date : November 2014
Estimated Primary Completion Date : December 2022
Estimated Study Completion Date : December 2023

Resource links provided by the National Library of Medicine

Family Hypercholesterolemia in cardiology

Primary Outcome Measures :
  1. Frequency of the Family Hypercholesterolemia in cardiology [ Time Frame: 1 day ]
    Number of Family Hypercholesterolemia among patients with LDL-C> 1.9g / l without hypoglycemic treatment or> 1.6g / l in lipid-lowering therapy

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The study is proposed to cardiology services hospitals. Aged 18 or more, seen in cardiology (USIC, Hospitalization, Consultation), who agreed to participate in the observatory, and coronary patients who have LDL-c levels

Inclusion Criteria:

  • coronary patients
  • who agreed to participate
  • high LDL-c levels: * LDL-c> = 1.9g / l without lipid lowering treatment according to the diagnostic score of Family Hypercholesterolemia these coronary patients with LDL> 1.9g / l may possibly or probably be achieved Hypercholesterolemia Family.


* LDL-c> = 1.6g / l in lipid-lowering treatment, the reduction of LDL-c average expected under standard lipid-lowering therapy (statin alone) being 30-40% of these patients had therefore pretreatment levels greater than 2 g / l or greater than 2.5 g / l and may possibly or probably be achieved Family Hypercholesterolemia after the diagnostic score.

Exclusion Criteria:

  • Expressed refusal to participate in the observatory
  • Age ≤ 18

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02013713

European Hospital Georges Pompidou
Paris, France, 75015
Sponsors and Collaborators
French Cardiology Society

Responsible Party: French Cardiology Society Identifier: NCT02013713     History of Changes
Other Study ID Numbers: 12 449
First Posted: December 17, 2013    Key Record Dates
Last Update Posted: November 24, 2017
Last Verified: November 2017

Keywords provided by French Cardiology Society:
Family Hypercholesterolemia

Additional relevant MeSH terms:
Hyperlipoproteinemia Type II
Lipid Metabolism Disorders
Metabolic Diseases
Lipid Metabolism, Inborn Errors
Metabolism, Inborn Errors
Genetic Diseases, Inborn