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Can Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation Improve Survival of out-of Hospital Cardiac Arrest?

This study is currently recruiting participants.
Verified October 2017 by Sang Do Shin, Seoul National University Hospital
Sponsor:
ClinicalTrials.gov Identifier:
NCT02010151
First Posted: December 12, 2013
Last Update Posted: October 19, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Collaborators:
Korean Center for Disease Control and Prevention
Seoul Metropolitan Government Health and Welfare Office
Seoul Metropolitan Fire and Disaster Headquater
Korea Association for Safety Community
Information provided by (Responsible Party):
Sang Do Shin, Seoul National University Hospital
  Purpose
The hypothesis of this study is Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation (NAD-CPR) would improve survival of out-of-hospital cardiac arrest (OHCA).

Condition Intervention
Out of Hospital Cardiac Arrest Other: NAD-CPR

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: Population Based Intervention Trial of Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation

Resource links provided by NLM:


Further study details as provided by Sang Do Shin, Seoul National University Hospital:

Primary Outcome Measures:
  • Survival to discharge [ Time Frame: 40 months ]
    difference of survival to discharge rate of before intervention period (20 months) and intervention period (20 months)


Secondary Outcome Measures:
  • Pre-hospital return of spontaneous circulation (ROSC) [ Time Frame: 40 months ]
    difference of pre-hospital ROSC rate of before intervention period (20 months)and intervention period (20 months)

  • survival to admission [ Time Frame: 40 months ]
    difference of survival to admission rate of before intervention period (20 months)and intervention period (20 months)

  • good neurological recovery [ Time Frame: 40 months ]
    Cerebral performance category 1 or 2 is defined as good neurological recovery. Secondary outcome is difference of good neurological recovery rate of before intervention period (20 months)and intervention period (20 months).


Estimated Enrollment: 3776
Study Start Date: March 2015
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: December 2017 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: NAD-CPR
When dispatcher detects a patient with OHCA, the dispatcher activates trained neighborhoods by informing events nearby using short message service via cellular phone. The neighborhood within geographically accessible area who could perform effective CPR and defibrillation would be alerted with event of OHCA and the nearest AED.
Other: NAD-CPR
When Dispatcher detects OHCA, short message service (SMS)about the OHCA event and information about the location of nearest AED is sent to trained laypersons within geographically accessible area.
No Intervention: Conventional dispatcher assisted CPR
When dispatcher detects OHCA, they instruct the caller with CPR instructions. This is conventional dispatcher assisted CPR performed in Seoul.

Detailed Description:
Out-of-hospital cardiac arrest (OHCA) is a major health problem, occurring in about 1 in 1,500 adults in the developed countries each year. Although layperson CPR and defibrillation are crucial components of chain of survival, layperson CPR rate and it's quality is low and public-access defibrillation (PAD) program is not cost-effective.If trained bystanders can know the information of occurrence of OHCA and nearest place for automated external defibrillator (AED) at the same time by dispatch center, these neighborhoods could run and give high quality CPR and early defibrillation. If this protocol ,Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation(NAD-CPR), is introduced to community, it may improve survival of OHCA.
  Eligibility

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Ages Eligible for Study:   15 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • all OHCA with presumed cardiac etiology more than 15 years old
  • assessed by emergency medical service (EMS) providers dispatched by dispatch center
  • dispatcher detected OHCA patients

Exclusion Criteria:

  • OHCA with non-cardiac etiology
  • prolonged cardiac arrest with a suspected duration more than 30 minutes
  • cases with rigor mortis or rivor mortis, decapitated or decomposed body
  • Non detected cases by dispatcher
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02010151


Contacts
Contact: Soyeon Kong, PhD 28220724412 soyeon.kong@gmail.com

Locations
Korea, Republic of
Seoul Metropolitan City Recruiting
Seoul, Korea, Republic of
Sub-Investigator: Kyoung Jun Song, MD         
Sub-Investigator: Eui Jung Lee, MD         
Sub-Investigator: Joo Yeong Kim, MD         
Sub-Investigator: Yu Jin Lee, MD         
Sub-Investigator: Ju Ok Park, MD         
Sub-Investigator: Ki Jeong Hong, MD         
Sub-Investigator: So Young Ha, MD         
Sub-Investigator: Kwang Soo Bae, MD         
Sub-Investigator: Jeong Eun Kim, MPH         
Sponsors and Collaborators
Seoul National University Hospital
Korean Center for Disease Control and Prevention
Seoul Metropolitan Government Health and Welfare Office
Seoul Metropolitan Fire and Disaster Headquater
Korea Association for Safety Community
Investigators
Principal Investigator: Sang Do Shin, MD, PhD Seoul National University Hospital
  More Information

Responsible Party: Sang Do Shin, Associated Professor, Seoul National University Hospital
ClinicalTrials.gov Identifier: NCT02010151     History of Changes
Other Study ID Numbers: SNUEMS201309
First Submitted: December 9, 2013
First Posted: December 12, 2013
Last Update Posted: October 19, 2017
Last Verified: October 2017

Keywords provided by Sang Do Shin, Seoul National University Hospital:
Out of Hospital Cardiac Arrest
Cardiopulmonary Resuscitation
dispatch
emergency medicine

Additional relevant MeSH terms:
Heart Arrest
Out-of-Hospital Cardiac Arrest
Heart Diseases
Cardiovascular Diseases