Influence of Stroke on the Composition of Intestinal Microbiota (GUTSTROKE)
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|ClinicalTrials.gov Identifier: NCT02008604|
Recruitment Status : Completed
First Posted : December 11, 2013
Last Update Posted : November 29, 2018
|Condition or disease|
|Stroke Transient Ischemic Attack (TIA)|
|Study Type :||Observational|
|Actual Enrollment :||24 participants|
|Official Title:||Influence of Stroke on the Composition of Intestinal Microbiota (GUTSTROKE)|
|Actual Study Start Date :||June 2014|
|Actual Primary Completion Date :||April 2018|
|Actual Study Completion Date :||April 2018|
patients with a transient ischemic attack (control group)
- composition of intestinal microbiome [ Time Frame: change between day 1, day 4, day 7, day 14 after stroke ]The composition of the intestinal metagenome / microbiome will be determined by analyzing the 16S rRNA by 454 Pyrosequencing.
- test of correlation between most changed group of bacteria with changes in immunological parameters (HLA-DR) [ Time Frame: days 1, 4, 7 after stroke ]Analysis of correlation between changes in microbiome (most changed group of bacteria, e.g. lactobacilli) with changes in immunological parameters (e.g. HLA-DR, IL-6, IL-10, CD4-lymphocytes from blood samples).
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02008604
|Charite Universitätsmedizin Berlin|
|Berlin, Germany, 10117|
|Principal Investigator:||Andreas Meisel, Prof. Dr.||Charite University, Berlin, Germany|