Effect of Goal-directed Fluid Therapy Using Stroke Volume Variation in Patients Undergoing Free Flap Reconstruction After Head and Neck Cancer Resection
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|ClinicalTrials.gov Identifier: NCT02003066|
Recruitment Status : Unknown
Verified November 2015 by Yonsei University.
Recruitment status was: Recruiting
First Posted : December 6, 2013
Last Update Posted : November 30, 2015
|Condition or disease||Intervention/treatment||Phase|
|General Anesthesia||Procedure: Standard fluid therapy Procedure: Conservative fluid therapy||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||62 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Outcomes Assessor)|
|Study Start Date :||November 2013|
|Estimated Primary Completion Date :||November 2016|
|Estimated Study Completion Date :||November 2016|
Procedure: Standard fluid therapy
In Standard fluid therapy group, the administration of fluid will be guided to maintain mean blood pressure more than 65 mmHg, urine output more than 0.5 ml/kg/hr, and central venous pressure less than 14 mmHg.
|Active Comparator: Conservative||
Procedure: Conservative fluid therapy
In Goal directed fluid therapy group, the administration of fluid will be guided by stroke volume variation. The anesthesiologist will infuse volulyte (Fresenius Kabi, Bad Homburg, Germany) 200 ml if stroke volume variation is over 12%. If cardiac index is below 2.5 l/min/m2 and stroke volume variation is below 12%, start dobutamine.
- Length of hospital stay [ Time Frame: 1 month after surgery ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02003066
|Contact: Bon-Nyeo Koo, MDfirstname.lastname@example.org|
|Korea, Republic of|
|Department of Anesthesiology and Pain Medicine, Yonsei University Health System||Recruiting|
|Seoul, Korea, Republic of, 120-752|
|Contact: Bon-Nyeo Koo, MD 82-2-2228-2420 email@example.com|