Optical Coherence Tomography (OCT) in Retinal Vasculitis
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|ClinicalTrials.gov Identifier: NCT01998464|
Recruitment Status : Active, not recruiting
First Posted : November 29, 2013
Last Update Posted : April 9, 2020
Retinal vasculitis is a sight-threatening inflammation that involves the blood vessels of the retina, the tissue that lines the inside of the eye. This inflammation may occur on its own or as a result of an infectious, cancerous, or inflammatory disorder.
Optical coherence tomography (OCT) is an imaging technology that can perform non-contact cross-sectional imaging of retinal and choroidal tissue structure in real time. It is similar to ultrasound imaging, except that OCT measures the intensity of reflected light rather than sound waves.
The purpose of this study is to see if non-invasive OCT technology can diagnose retinal vasculitis as well as the more invasive fluorescein angiography, which requires an injection of dye into the vein of an arm of a patient. The study will also compare the mapping of blood vessels (angiography) and loss of blood flow (ischemia) by fluorescein angiography and OCT.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||12 participants|
|Official Title:||Evaluation of the Utility of OCT Angiography in Assessing Vascular Perfusion in Retinal Vasculitis|
|Study Start Date :||January 2014|
|Estimated Primary Completion Date :||December 2021|
|Estimated Study Completion Date :||December 2021|
Retinal Vasculitis Group
Up to 35 patients diagnosed with retinal vasculitis will be considered and evaluated for enrollment in this study.
- Blood flow patterns in retinal vasculitis [ Time Frame: 24 months ]To determine if identifying early changes in blood vessel patterns will aid in early diagnosis and treatment of retinal vasculitis. Total retinal blood flow will be measured in uL/min.
- Ischemia in retinal vasculitis [ Time Frame: 24 months ]To determine if identifying lost or reduced blood flow will aid in early diagnosis and treatment of retinal vasculitis. Non-perfusion area will be measured in mm2.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01998464
|United States, Oregon|
|Portland, Oregon, United States, 97239|
|Principal Investigator:||Phoebe Lin, MD, PhD||Oregon Health and Science University|