Prevalence of MTHFR Polymorphisms in Venous Disease
The etiologies of varicose veins and the progression to more serious forms of chronic venous disease and identification of appropriate diagnostic tests to better aid patient management by identifying individuals who may benefit from more aggressive treatment and/ or prophylactic measures.
|Study Design:||Observational Model: Cohort
Time Perspective: Cross-Sectional
|Official Title:||Prevalence of MTHFR Polymorphisms in Venous Disease With or Without Concomitant Thrombosis|
- Prevalence of MTHFR mutation between patients [ Time Frame: Baseline ] [ Designated as safety issue: No ]Determine whether the prevalence of the MTHFR mutation differs between patient with varicose veins compared to controls and with or without superficial vein thrombosis.
Biospecimen Retention: Samples With DNA
Whole blood and serum
|Study Start Date:||February 2011|
|Study Completion Date:||November 2014|
|Primary Completion Date:||November 2014 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01993914
|United States, California|
|The Elite Laser Vein Center|
|Los Angeles, California, United States, 90025|
|Principal Investigator:||Michael Richman, MD,FACS,FCCP|