Determination of Adipocytokine in Synovial Fluid of Osteoarthritis Patients
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01993342|
Recruitment Status : Unknown
Verified November 2013 by Joan Calvet Fontova, Hospital Parc Taulí, Sabadell.
Recruitment status was: Recruiting
First Posted : November 25, 2013
Last Update Posted : November 25, 2013
|Condition or disease||Intervention/treatment|
|Osteoarthritis||Other: arthrocentesis Other: ultrasonography of the knee|
|Study Type :||Observational|
|Estimated Enrollment :||35 participants|
|Official Title:||Determination of Adipocytokine in Synovial Fluid of Osteoarthritis Patients With Joint Pain and Effusion|
|Study Start Date :||October 2013|
|Estimated Primary Completion Date :||November 2013|
|Estimated Study Completion Date :||March 2014|
Inflammatory knee osteoarthritis
We recruited patients with osteoarthritis and synovial effusion to diagnostic the effusion and to confirm that this this synovial fluid had mechanical characteristics. Now we are going to determine the adipocytokines and traditional parameters of inflammation in this synovial fluid to correlate it, and we will associate it with the ultrasound explanation of the knee that we have in our database.
The made a diagnostic arthrocentesis to all patient we included
Other: ultrasonography of the knee
We explored the affected knee with an ultrasound explanation in order to describe inflammatory changes based on standard examination.
- Determination of adipocytokine levels (adiponectin, leptin, resistin, visfatin, osteopontin) in synovial fluid [ Time Frame: We determine adipocytoquines in one month, all patients in the same determination kit ]We have all the synovial fluid freeze, so now we have to determine the levels of everyone.
- Knee inflammation parameters detected by ultrasonography [ Time Frame: three months ]We performed the ultrasonography evaluation at the same time than the visit were realized, and we have the results in a data base, so we will wait for the adipocytokine results and we will compare with ultrasound evaluation
- To determine additional classic parameters of inflammation in synovial fluid as Interleukine 1 beta, Interleukine 6 and tumor necrosis factor alfa [ Time Frame: We determine this inflammatory parameters in one month in all patient at the same time ]We will use classic inflammation parameters to compare with adipocytokine levels
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01993342
|Contact: Joan Calvet, Dr||0034 937231010 ext email@example.com|
|Contact: Cristobal Orellana, Dr||0034 937231010 ext firstname.lastname@example.org|
|Hospital Parc Tauli Sabadell||Recruiting|
|Sabadell, Barcelona, Spain, 08208|
|Contact: Joan Calvet, Dr 0034937231010 ext 24065 email@example.com|
|Contact: Cristobal Orellana, Dr 0034937231010 ext 24065 firstname.lastname@example.org|
|Principal Investigator: Joan Calvet, Dr|
|Sub-Investigator: Cristobal Orellana, Dr|
|Sub-Investigator: Maria Garcia-Manrique, Dra|
|Sub-Investigator: Noemi Navarro, Dra|
|Principal Investigator:||Joan Calvet, Dr||Hospital Parc Tauli|
|Study Director:||Cristobal Orellana, Dr||Hospital Parc Tauli|