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Photometric Stereo Endoscopy (PSE) as a Tool for Imaging the Rectum and Colon

This study has been completed.
Information provided by (Responsible Party):
Norman Nishioka, MD, Massachusetts General Hospital Identifier:
First received: November 4, 2013
Last updated: March 22, 2017
Last verified: September 2014
The goal of this research is to assess photometric stereo endoscopy (PSE) as an endoscopic imaging technique. Specifically, topographical surface contrast reconstructed from the PSE data will be compared to conventional imaging contrast to assess if PSE provides enhanced contrast of abnormal tissue.

Condition Intervention
Colonic Polyps
Device: PSE

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: No masking
Primary Purpose: Diagnostic
Official Title: Pilot Study to Evaluate Photometric Stereo Endoscopy (PSE) as a Tool for Imaging the Rectum and Colon

Resource links provided by NLM:

Further study details as provided by Massachusetts General Hospital:

Primary Outcome Measures:
  • Image Contrast [ Time Frame: Immediate ]
    Comparison of image contrast obtained using standard colonoscopy and PSE.

Estimated Enrollment: 30
Study Start Date: November 2013
Study Completion Date: July 2014
Primary Completion Date: June 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: PSE
Patients whose distal colon is imaged using the PSE device. This is a pilot trial of 30 patients.
Device: PSE
Other Name: photometric stereo endoscopy


Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients undergoing a routine colonoscopy screening
  • Patients must be over the age of 18
  • Patients must be able to give informed consent

Exclusion Criteria:

  • Patients with bleeding/hemostasis disorders
  • Patients that are pregnant
  • Patients taking any anti-coagulants that would preclude them from undergoing a standard of care colonoscopy, such as Coumadin and Plavix, at the time of the study
  • Patients with known colitis or active bleeding will be excluded
  Contacts and Locations
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Please refer to this study by its identifier: NCT01979458

United States, Massachusetts
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Sponsors and Collaborators
Massachusetts General Hospital
  More Information

Responsible Party: Norman Nishioka, MD, Physician, Massachusetts General Hospital Identifier: NCT01979458     History of Changes
Other Study ID Numbers: 2013P001115
Study First Received: November 4, 2013
Last Updated: March 22, 2017

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Massachusetts General Hospital:

Additional relevant MeSH terms:
Colonic Polyps
Intestinal Polyps
Pathological Conditions, Anatomical processed this record on May 22, 2017