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Stem Cell Therapy for Cerebral Palsy

This study has been completed.
Information provided by (Responsible Party):
Neurogen Brain and Spine Institute Identifier:
First received: October 25, 2013
Last updated: September 23, 2016
Last verified: October 2013
the purpose of this study was to study the effect of stem cell therapy on common symptoms of cerebral palsy patients.

Condition Intervention Phase
Cerebral Palsy
Procedure: Autologous bone marrow mononuclear cell transplantation
Phase 1

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Open Label Study of Autologous Bone Marrow Mononuclear Cells in Cerebral Palsy

Resource links provided by NLM:

Further study details as provided by Neurogen Brain and Spine Institute:

Primary Outcome Measures:
  • Change in clinical symptoms of cerebral palsy after 6 months [ Time Frame: Six months ]

Enrollment: 40
Study Start Date: August 2010
Study Completion Date: August 2013
Primary Completion Date: August 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: stem cell
autologous bone marrow mononuclear cell transplantation
Procedure: Autologous bone marrow mononuclear cell transplantation


Ages Eligible for Study:   17 Months to 22 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Diagnosed cases of any type of Cerebral Palsy
  • age above 12 months.

Exclusion Criteria:

  • presence of acute infections such as Human immunodeficiency virus/Hepatitis B Virus/Hepatitis C Virus
  • malignancies
  • bleeding tendencies
  • pneumonia
  • renal failure
  • severe liver dysfunction
  • severe anemia [Hemoglobin < 8]
  • any bone marrow disorder
  • space occupying lesion in brain
  • other acute medical conditions such as respiratory infection and pyrexia.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01978821

Neurogen brain and spine institute
Mumbai, Maharashtra, India, 400071
Sponsors and Collaborators
Neurogen Brain and Spine Institute
  More Information

Additional Information:
Responsible Party: Neurogen Brain and Spine Institute Identifier: NCT01978821     History of Changes
Other Study ID Numbers: NGBSI-01
Study First Received: October 25, 2013
Last Updated: September 23, 2016

Keywords provided by Neurogen Brain and Spine Institute:
Cerebral Palsy
autologous bone marrow mononuclear cells
stem cell therapy

Additional relevant MeSH terms:
Cerebral Palsy
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Brain Damage, Chronic
Brain Diseases
Central Nervous System Diseases processed this record on May 25, 2017