Brain Mechanisms of Human Motivation
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01976975|
Recruitment Status : Completed
First Posted : November 6, 2013
Last Update Posted : March 23, 2018
|Condition or disease|
|Major Depressive Disorder Bipolar Disorder|
|Study Type :||Observational|
|Actual Enrollment :||270 participants|
|Official Title:||Multi Level Analysis of Positive Valence Systems Across Mood Disorders|
|Study Start Date :||October 2013|
|Actual Primary Completion Date :||January 2018|
|Actual Study Completion Date :||January 2018|
Mood disorder patients
Patients with depressive and/or manic or hypomanic symptoms
Participants with no lifetime history of psychiatric illness
- Behavioral Performance in Probabilistic Reward Task [ Time Frame: Given once during the second session for a total of 10 minutes ]The probabilistic reward task is designed to measure sensitivity to reward and reward learning. It will be administered three times during session 1 to calculate changes in reward sensitivity.
- Behavioral Performance in Instrumental Learning Task [ Time Frame: Administered in session 3 during two hour long scan ]The instrumental learning task is designed to measure participant learning from reward and punishment.
- Symptom severity [ Time Frame: 6 months ]Participants will report on the phone about their symptom severity after completing all sessions.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01976975
|United States, Massachusetts|
|Belmont, Massachusetts, United States, 02478|
|Principal Investigator:||Diego A Pizzagalli, Ph.D.||Mclean Hospital|