The Effect of Aerobic Exercise Training for Migraine Prevention.
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|ClinicalTrials.gov Identifier: NCT01972607|
Recruitment Status : Completed
First Posted : October 30, 2013
Last Update Posted : April 11, 2016
|Condition or disease||Intervention/treatment||Phase|
|Headache Disorders, Primary||Other: Exercise Training||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||60 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||The Effect of Aerobic Exercise Training for Migraine Prevention.|
|Study Start Date :||March 2012|
|Actual Primary Completion Date :||March 2015|
|Actual Study Completion Date :||March 2016|
No Intervention: CONTROL
This group will receive the same treatment of the experimental group after the test-retest measurements.
This group will receive the treatment with aerobic exercise training
Other: Exercise Training
12 weeks of aerobic exercise training performed 3x/week at moderate intensity with sessions of 40 min.
- Frequency of Migraine/month [ Time Frame: Migraine frequency measured between 4th and 8th weeks has been set as the "baseline" period, and will be compared to changes in frequency measured between weeks 12 to 16, which has been set as "post-intervention" period. ]
- Plasma levels of anandamide, cytokines and aminopeptidases [ Time Frame: Resting plasma levels measured between 4th and 8th weeks has been set as the "baseline" levels, and will be compared to changes in resting levels measured between weeks 12 to 16, set as the "post-intervention" levels. ]
- Days with Migraine [ Time Frame: Days with migraine measured between 4th and 8th weeks has been set as the "baseline" period, and will be compared to changes in days with migraine measured between weeks 12 to 16, which has been set as "post-intervention" period ]
- Maximal Oxygen Uptake [ Time Frame: Measurements of the maximal oxygen uptake has been performed at Week 1, which is set as "baseline" measurement, and at week 16, which is set as "post-intervention" measurement. ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01972607
|Federal University of Sao Paulo|
|São Paulo, SP, Brazil, 04021-001|
|Study Chair:||Mario FP Peres, MD, PhD||Federal University of Sao Paulo|