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Restless Legs Syndrome in Stroke Patients

This study has been completed.
Information provided by (Responsible Party):
Dr. Ilana Schlesinger, Rambam Health Care Campus Identifier:
First received: September 15, 2013
Last updated: October 17, 2013
Last verified: October 2013
Our study aimed to examine a possible association between Restless legs syndrome and cerebrovascular disease, by examining patients during hospitalization for acute stroke or transient ischemic attack, in a matched case-control design.

Restless Legs Syndrome
Transient Ischemic Attack

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Restless Legs Syndrome in Stroke Patients

Resource links provided by NLM:

Further study details as provided by Rambam Health Care Campus:

Primary Outcome Measures:
  • Prevalence of Restless legs syndrome in patients with stroke or Transient ischemic attack vs. prevalence in controls. [ Time Frame: At time of interview ]
    The frequency (prevalence) of restless leg syndrome (RLS) in patients who have suffered stroke or TIA will be compared to that of subjects who have not suffered stroke or TIA (controls). The two groups will be stratified with regard to age and gender. Statistical comparison will be made by univariate analyses and by multivariate logistic regression analyses (which will include cerebrovascular risk factors besides stroke or TIA).

Enrollment: 447
Study Start Date: January 2008
Study Completion Date: December 2008
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Patients with stroke or transient ischemic attack
Interview regarding restless legs syndrome
Subjects without stroke or transient ischemic attack
Interview regarding restless legs syndrome


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients hospitalized with stroke or transient ischemic attack.

Inclusion Criteria:

  • 18 years old or older
  • Hospitalization for stroke or transient ischemic attack

Exclusion Criteria:

  • 18 years old or younger
  • No stroke or transient ischemic attack
  Contacts and Locations
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Please refer to this study by its identifier: NCT01967303

Sponsors and Collaborators
Rambam Health Care Campus
Principal Investigator: Ilana Schlesinger Rambam Health Care Campus, Haifa, Israel
  More Information

Responsible Party: Dr. Ilana Schlesinger, Director, Movement Disorders Center, Rambam Health Care Campus Identifier: NCT01967303     History of Changes
Other Study ID Numbers: 3186
Study First Received: September 15, 2013
Last Updated: October 17, 2013

Keywords provided by Rambam Health Care Campus:
Restless legs syndrome
Transient ischemic attack
Cerebrovascular risk factors

Additional relevant MeSH terms:
Ischemic Attack, Transient
Brain Ischemia
Psychomotor Agitation
Restless Legs Syndrome
Pathologic Processes
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Neurologic Manifestations
Psychomotor Disorders
Neurobehavioral Manifestations
Signs and Symptoms
Sleep Disorders, Intrinsic
Sleep Wake Disorders
Mental Disorders processed this record on May 25, 2017