Causative Diagnosis on Prosthetic Joint Infections: Establishment of a Comprehensive Diagnostic Strategy
On joint orthopaedic hardware infections are one of the most frequently encountered complications in orthopaedic surgery. However 6% of the cultures remain sterile, etiological diagnosis cannot be established despite obvious signs of infection. As part of this research project, we have developed a new strategy diagnosis including directly the use of PCR to reduce the number of negative results. This should have a major therapeutic impact in terms of timeliness and specificity of antibiotic.
Evaluate the effectiveness of the new diagnostic strategy on etiological identification of prosthesis infections.
Minimum 6 percent increase in the number of patients with an etiological diagnosis of infection on prosthesis.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
|Official Title:||Causative Diagnosis on Prosthetic Joint Infections: Establishment of a Comprehensive Diagnostic Strategy|
- Bone biopsies multisite [ Time Frame: 4 years ] [ Designated as safety issue: No ]Increase of at least 6% of patients with an etiologic diagnosis of prosthesis infection established.
|Study Start Date:||October 2013|
|Estimated Study Completion Date:||April 2018|
|Estimated Primary Completion Date:||October 2017 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01957228
|Contact: andreas firstname.lastname@example.org|
|Assistance Publique Hopitaux de Marseille||Recruiting|
|Marseille, France, 13354|
|Contact: andreas stein email@example.com|
|Principal Investigator: andreas stein|
|Study Director:||LOIC MONDOLONI||Assistance Publique Hopitaux De Marseille|