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Effect of Chronic Catecholamine Overproduction on Brown Adipose Tissue

This study is currently recruiting participants. (see Contacts and Locations)
Verified October 2016 by University of Aarhus
Information provided by (Responsible Party):
Esben Søndergaard, University of Aarhus Identifier:
First received: September 20, 2013
Last updated: October 26, 2016
Last verified: October 2016
  • To investigate the effect of catecholamine excess on brown fat.
  • To evaluate the effect of brown fat on energy expenditure and lipid and glucose metabolism

Condition Intervention
Adrenal Incidentaloma
Procedure: Removal of adrenal tumor

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Effect of Chronic Catecholamine Overproduction on Brown Adipose Tissue

Resource links provided by NLM:

Further study details as provided by University of Aarhus:

Primary Outcome Measures:
  • [18F]FDG uptake in brown adipose tissue [ Time Frame: 3 months ]

Biospecimen Retention:   Samples With DNA
Blood and adipose tissue samples

Estimated Enrollment: 15
Study Start Date: August 2013
Estimated Study Completion Date: January 2019
Estimated Primary Completion Date: January 2019 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Pheochromocytoma patients
Pheochromocytoma patients
Procedure: Removal of adrenal tumor
Incidentaloma patients
Incidentaloma patients
Procedure: Removal of adrenal tumor


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with adrenal tumors

Inclusion Criteria:

  • 10 patients with pheochromocytoma
  • 5 patients with incidentaloma without hormone production
  • Age > 18 years

Exclusion Criteria:

- None

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01949714

Contact: Esben Søndergaard, MD, PhD 4578461631

Department of Endocrinology MEA, Aarhus Hospital Recruiting
Aarhus C, Please Select, Denmark, 8000
Contact    4578461631      
Principal Investigator: Esben Søndergaard, MD, PhD         
Sponsors and Collaborators
University of Aarhus
  More Information

Responsible Party: Esben Søndergaard, MD, PhD, Post Doc, University of Aarhus Identifier: NCT01949714     History of Changes
Other Study ID Numbers: ES-0005
Study First Received: September 20, 2013
Last Updated: October 26, 2016

Additional relevant MeSH terms:
Adrenocortical Adenoma
Neuroendocrine Tumors
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms, Nerve Tissue
Adrenal Cortex Neoplasms
Adrenal Gland Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Adrenal Cortex Diseases
Adrenal Gland Diseases
Endocrine System Diseases processed this record on May 25, 2017