Transfusion Reaction by Washed Red Blood Cell (RBC)

This study is currently recruiting participants. (see Contacts and Locations)
Verified April 2016 by Seoul National University Bundang Hospital
Information provided by (Responsible Party):
Hyo-Seok Na, Seoul National University Bundang Hospital Identifier:
First received: August 22, 2013
Last updated: April 18, 2016
Last verified: April 2016
The hypothesis is that transfusion of washed red blood cell can decrease the complication by transfusion.

Condition Intervention
Avascular Necrosis of Hip.
Degenerative Arthritis, Hip.
Osteoarthritis, Hip.
Developmental Dislocation of Hip.
Dysplastic Hip.
Other: Washing of packed RBC by normal saline

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Prevention

Resource links provided by NLM:

Further study details as provided by Seoul National University Bundang Hospital:

Primary Outcome Measures:
  • Complication by transfusion [ Time Frame: Operation day and during postoperative 5 days ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • Total units of RBC transfused. [ Time Frame: On the operation day and during the postoperative 5 days ] [ Designated as safety issue: No ]
  • Hemoglobin [ Time Frame: 1 day before the operation day and postoperative 1 day ] [ Designated as safety issue: No ]

Estimated Enrollment: 223
Study Start Date: August 2013
Estimated Primary Completion Date: December 2016 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: washed RBC
Packed RBCs are Washed and then, transfused.
Other: Washing of packed RBC by normal saline
No Intervention: pack RBC
Packed RBCs are transfused.


Ages Eligible for Study:   20 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients undergoing total hip replacement arthroplasty

Exclusion Criteria:

  • Patients who do not agree with this clinical study.
  • Patients who have a history of transfusion for recent 1 month.
  • Patients who have rare blood types.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01934907

Contact: Hyo-Seok Na, PhD. 82 31 787 7507

Korea, Republic of
Seoul National University Bundang Hospital Recruiting
Seongnam, Gyeonggi, Korea, Republic of, 443-607
Contact: Hyo-Seok Na    82 31 787 7507   
Principal Investigator: Hyo-Seok Na         
Sponsors and Collaborators
Seoul National University Bundang Hospital
  More Information

Responsible Party: Hyo-Seok Na, Dr., Seoul National University Bundang Hospital Identifier: NCT01934907     History of Changes
Other Study ID Numbers: B-1307/212-009 
Study First Received: August 22, 2013
Last Updated: April 18, 2016
Health Authority: South Korea: Institutional Review Board

Additional relevant MeSH terms:
Hip Injuries
Hip Dislocation
Hip Dislocation, Congenital
Osteoarthritis, Hip
Congenital Abnormalities
Joint Diseases
Musculoskeletal Abnormalities
Musculoskeletal Diseases
Rheumatic Diseases
Wounds and Injuries processed this record on May 26, 2016