Improved Fertility After Exercise in Overweight/Obese Women (FertilEX)
|ClinicalTrials.gov Identifier: NCT01933633|
Recruitment Status : Terminated (Enrollment proceeded to slowly)
First Posted : September 2, 2013
Last Update Posted : December 21, 2017
|Condition or disease||Intervention/treatment|
|Obesity Infertility, Female||Behavioral: Exercise|
Obesity is associated with several diseases, as type 2 diabetes, cardiovascular disease and some types of cancer, this is of great concern for the public health. Also, of more immediate importance for these women; obesity is associated with increased risks of sub-fertility. The overall aim of the current project is to expand the knowledge about effective interventions to prevent the increasing prevalence of obesity-associated sub-fertility in population.
One cause of the increased referral rate for in-vitro fertilization is the growing prevalence of overweight and obesity. Currently, about 700 couples are annually referred for in-vitro fertilization at St.Olav's Hospital. In this interdisciplinary trial, involving physiotherapists, exercise physiologists, gynecologists, and basic researchers, the effects of regular high intensity exercise training on fertility in sub-fertile overweight and obese women will be investigated.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||18 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Study of Pregnancy Rate After Exercise Training Prior to Assisted Fertilisation in Overweight/Obese Women|
|Actual Study Start Date :||September 2013|
|Primary Completion Date :||December 2017|
|Study Completion Date :||December 2017|
Regular exercise training for 10 weeks prior to assisted fertilisation
No Intervention: Control
- Pregnancy rate [ Time Frame: 7 weeks after assisted fertilisation ]The primary outcome measure is ongoing pregnancy, defined as the sonographic evidence of intrauterine gestational sac and fetal heart activity at seven weeks of gestation.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01933633
|St Olavs Hospital|
|Principal Investigator:||Trine Moholdt, PhD||Norwegian University of Science and Technology|