Eye Pressure Lowering Surgery (IOP)
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|ClinicalTrials.gov Identifier: NCT01931904|
Recruitment Status : Recruiting
First Posted : August 30, 2013
Last Update Posted : April 12, 2018
|Condition or disease|
Using high-speed ocular coherence tomography (OCT) systems, we have developed new methods to image and measure optic nerve head (ONH) and retinal blood flow. Preliminary results have shown that visual field (VF) loss is more highly correlated with retinal blood flow as measured by OCT than any neural structure measured by OCT or other imaging modality. Accordingly, the goal of the proposed project is to improve the diagnostic and prognostic evaluation of glaucoma by further developing novel functional OCT measurements using ultrahigh-speed (70-100 kHz) OCT technology.
Retinal blood flow, ONH circulation, optic disc rim volume, peripapillary nerve fiber layer volume, and macular ganglion cell complex volume are all pieces of the same glaucoma puzzle. This project will develop novel imaging methods that allow us to look at the whole picture using one tool - ultrahigh-speed OCT.
|Study Type :||Observational|
|Estimated Enrollment :||46 participants|
|Official Title:||Observational Study of Ocular Blood Flow Pre- and Post- Glaucoma Surgery Using Functional and Structural Optical Coherence Tomography|
|Study Start Date :||February 2014|
|Estimated Primary Completion Date :||December 2022|
|Estimated Study Completion Date :||December 2022|
Trabeculectomy or Tube Shunt Patients
46 glaucoma patients undergoing trabeculectomy or tube shunt surgery to lower IOP
- Effects of Intraocular Pressure (IOP) Reduction on Ocular Perfusion [ Time Frame: Subjects will be evaluated on enrollment (pre-operatively) and at post-operative visits ( 3, 6, 12, 18, and 24-months post-op). ]To determine if IOP reduction improves ocular perfusion.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01931904
|Contact: Rachel McClain, COAfirstname.lastname@example.org|
|Contact: Denny Romfh, ODemail@example.com|
|United States, Oregon|
|Portland, Oregon, United States, 97239|
|Contact: Rachel McClain, COA 503-494-9628 firstname.lastname@example.org|
|Contact: Denny Romfh, OD 503-494-4351 email@example.com|
|Sub-Investigator: Beth Edmunds, MD, PhD|
|Sub-Investigator: Mansi Parikh, MD|
|Sub-Investigator: Hana Takusagawa, MD|
|Sub-Investigator: Lorinna Lombardi, MD|
|Sub-Investigator: David Huang, MD, PhD|
|Sub-Investigator: Shandiz Tehrani, MD|
|Principal Investigator:||John Morrison, MD||Oregon Health and Science University|