Amnesia After Surgery for Anterior Communicating Aneurysm: High Resolution Magnetic Resonance (MR) Imaging Findings

This study has been completed.
Information provided by (Responsible Party):
Shunji MUGIKURA, Tohoku University Identifier:
First received: August 7, 2013
Last updated: NA
Last verified: August 2013
History: No changes posted
To clarify whether amnesia after treatment of anterior communicating aneurysm (ACoA)is related to infarcts caused by occlusion or damage of the perforating artery of the ACoA, we used 3.0-T 3D high resolution MR imaging to identify and localize infarcts in patients with amnesia following treatment of ACoA aneurysm.

Subarachnoid Hemorrhage
Cerebral Aneurysm

Study Type: Observational [Patient Registry]
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Target Follow-Up Duration: 6 Years
Official Title: Basal Forebrain Amnesia After Surgery for Anterior Communicating Aneurysm: High Resolution 3-dimensional (3D) Magnetic Resonance (MR) Imaging Findings

Resource links provided by NLM:

Further study details as provided by Tohoku University:

Primary Outcome Measures:
  • cerebral infarction identified and localized in the basal forebrain on MR imaging [ Time Frame: within 15 months from the aneurysmal treatment(an expected average 4 months) ] [ Designated as safety issue: No ]

Enrollment: 14
Study Start Date: December 2007
Study Completion Date: July 2013
Primary Completion Date: July 2013 (Final data collection date for primary outcome measure)
Detailed Description:

Cohort register is made by experienced neuropsychologists in our institute.

MR imaging and data storage is in the department of diagnostic radiology of our institute.

MR images are evaluated by two neuroradiologists using a work station.


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients with amnesia following surgical treatment of the ACoA aneurysm.

Inclusion Criteria:

Clinical diagnosis of Amnesia

Exclusion Criteria:

Severe decreased intellectual function

  Contacts and Locations
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Please refer to this study by its identifier: NCT01919775

Sponsors and Collaborators
Tohoku University
Study Director: Shoki Takahashi, Professor Department of Diagnostic Radiology, Tohoku University, Graduate School of Medicine, Sendai, Japan
  More Information

Responsible Party: Shunji MUGIKURA, Principal Investigator, Associate professor of Departmetn of Diagnostic radiology, Tohoku University Identifier: NCT01919775     History of Changes
Other Study ID Numbers: tohoku-ACoA amnesia MRI 
Study First Received: August 7, 2013
Last Updated: August 7, 2013
Health Authority: Japan: Institutional Review Board

Additional relevant MeSH terms:
Intracranial Aneurysm
Brain Diseases
Subarachnoid Hemorrhage
Cardiovascular Diseases
Central Nervous System Diseases
Cerebrovascular Disorders
Intracranial Arterial Diseases
Intracranial Hemorrhages
Memory Disorders
Mental Disorders
Nervous System Diseases
Neurobehavioral Manifestations
Neurocognitive Disorders
Neurologic Manifestations
Pathologic Processes
Signs and Symptoms
Vascular Diseases processed this record on May 26, 2016