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Trial record 16 of 17 for:    "Fibrous Dysplasia of Bone"

Natural History of Cherubism Observational Study

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01916772
First Posted: August 6, 2013
Last Update Posted: January 10, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
The Cleveland Clinic
  Purpose
To observe the natural history of cherubism.

Condition Intervention
Cherubism Other: no interventions

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Natural Hisotry of Cherubism Observational Study

Resource links provided by NLM:


Further study details as provided by The Cleveland Clinic:

Primary Outcome Measures:
  • Disease progression [ Time Frame: 10 years ]
    We will take a history and examine patients with cherubism and look for disease progression.


Secondary Outcome Measures:
  • patient growth [ Time Frame: 10 years ]
    We will measure height and weight

  • bone abnormalities [ Time Frame: 10 years ]
    We will take panorex radiographs.


Biospecimen Retention:   Samples With DNA
We may take blood or skin samples.

Enrollment: 33
Study Start Date: July 2013
Study Completion Date: September 2016
Primary Completion Date: September 2016 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
cherubism patients
no interventions
Other: no interventions
no interventions

Detailed Description:
The investigators will take a history and examine patients with cherubism to determine the natural history of the disease. The investigators also may take skin or blood samples (IRB approved 7256) from patients to learn more about this disorder.
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
We will see patients with cherubism
Criteria

Inclusion Criteria:

patients with cherubism

Exclusion Criteria:

patients without cherubism

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01916772


Locations
United States, Ohio
Cleveland Clinic
Cleveland, Ohio, United States, 44195
Sponsors and Collaborators
The Cleveland Clinic
Investigators
Principal Investigator: Steven Lietman The Cleveland Clinic
  More Information

Publications:
Responsible Party: The Cleveland Clinic
ClinicalTrials.gov Identifier: NCT01916772     History of Changes
Other Study ID Numbers: CCFO7256
First Submitted: July 25, 2013
First Posted: August 6, 2013
Last Update Posted: January 10, 2017
Last Verified: January 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Plan Description: There is no plan to share IPD.

Keywords provided by The Cleveland Clinic:
cherubism
bone tumors

Additional relevant MeSH terms:
Fibrous Dysplasia of Bone
Cherubism
Osteochondrodysplasias
Bone Diseases, Developmental
Bone Diseases
Musculoskeletal Diseases
Jaw Diseases
Stomatognathic Diseases
Maxillofacial Abnormalities
Craniofacial Abnormalities
Musculoskeletal Abnormalities
Congenital Abnormalities
Genetic Diseases, Inborn