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Taste Reward Processing in Pediatric Obesity

This study has been completed.
Information provided by (Responsible Party):
Cara Bohon, PhD, Stanford University Identifier:
First received: July 23, 2013
Last updated: January 4, 2016
Last verified: January 2016
The study aims to provide a better understanding of the neural influence of eating behavior in the development of childhood obesity. Children ages 4-8 will be recruited to examine fMRI brain response to pictures that signal delivery of a chocolate milkshake and to the taste itself. The brain response will be compared to body mass index percentile scores for each child to help us determine whether brain differences present in adolescents and adults with obesity are present in young children.

Pediatric Obesity

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Taste Reward Processing in Pediatric Obesity

Resource links provided by NLM:

Further study details as provided by Stanford University:

Primary Outcome Measures:
  • fMRI brain response to taste of chocolate milkshake [ Time Frame: Baseline ] [ Designated as safety issue: No ]
  • fMRI brain response to picture cue [ Time Frame: Baseline ] [ Designated as safety issue: No ]

Enrollment: 30
Study Start Date: September 2013
Study Completion Date: August 2015
Primary Completion Date: August 2015 (Final data collection date for primary outcome measure)
Children with BMI percentile of 85 or above.
Healthy Weight
Children with BMI percentile between 15 and 85.


Ages Eligible for Study:   4 Years to 8 Years   (Child)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Children ages 4-8

Inclusion Criteria:

  • ages 4-8
  • parent available to complete surveys in English

Exclusion Criteria:

  • no presence of metal in body
  • no claustrophobia
  • no psychiatric or neurological condition that will affect brain function
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01908153

United States, California
Stanford University Department of Psychiatry
Stanford, California, United States, 94305
Sponsors and Collaborators
Stanford University
Principal Investigator: Cara Bohon, PhD Stanford University
  More Information

Responsible Party: Cara Bohon, PhD, Assistant Professor, Stanford University Identifier: NCT01908153     History of Changes
Other Study ID Numbers: UL1TR000093 
Study First Received: July 23, 2013
Last Updated: January 4, 2016
Health Authority: United States: Institutional Review Board

Keywords provided by Stanford University:
Picture food type
Taste type

Additional relevant MeSH terms:
Pediatric Obesity
Nutrition Disorders
Body Weight
Signs and Symptoms processed this record on October 21, 2016